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- Pamphlet “Strategic Bases in the Pacific Plan for Trusteeship” by the Commission to Study the Organization of Peace. [Filed under AHP General Peace 1945-1960: Box #4.009, Folder #9.3]
- The serological properties of simple substances. XII. The reactions of antiserum homologous to the p-azophenyltrimethylammonium group. J. Am. Chem. Soc. 68 (February 1946): 250-255. Written by: David Pressman, Allan L. Grossberg, Leland H. Pence, and Linus Pauling. [Filed under: LP Publications, 1946p.3]
- Entry in Calendar: “Crellie got ready to go to Lido Isle” [in child's handwriting] [Filed under LP's Daily Calendar of Events, 1946, 1958-1966, 1968-1970, 1973-1979: Box #5.012, Folder 12.1]
- Letter from LP to AHP. [Filed under LP Safe: Box #1.017, Folder #17.41]
[from the Biltmore? Madison Avenue at 43rd Street, New York City. Note from Cliff 2/1/46]
I have arrived in New York in good shape. The Conants bad to go to a banquet last night and I had dinner with Dean Buck- also Bright W., EJ Cohn, Edsall, Lamb, Fieser, and Van Vleck- at the Soc. of Fellows. Our commitee met today- not very exciting- and then lunched with Conant. We visited the mineralogical museum, and I talked with Bright a while before having to leave to catch the train. All is going well- I've read the Guggenheim digests carefully.
Everyone sends love to you, including your Paddy
Tomorrow I'll see Moe. I've just arrived in New York- 10 P.M.
Our first Guggenheim meeting has gone along well. Moe, Wallace N., Dr Sabin, & Louie Wright were there. Aydelotte is in London, and EB Wilson in Glasgow- he has been retired at Harvard, and has a lectureship " " [in Glasgow]. We had lunch together, and dinner (except Miss Sabin).
I asked Moe's advice about the Eastman Professorship. He thinks it is wonderful, and he recommends our suggesting going over at Christmas. (He is Treasurer of the Eastman Trust.) He said AH Compton was E.D. for only two terms, and someone else for only one. He said that the house, now in bad repair after the Fishers has it during the war (renting our some rooms, too), will be repaired this summer; it is somewhat better in heating and baths than the usual English standard, and has some nice furniture, also plenty of room for the children and guests. He thinks that the Trust may provide servants- possibly we have to pay their wages. I think that we should plan on going about Christmas.
Louie is feeling grumpy because the Huntington trustees may get in a stuffed shirt as director; he feels that they are now getting along better than with one, and saving money.
Last night I was worried for a few minutes. After finishing my letter to you I opened my smaller bag- and it wasn't mine, but one very much like it, which I had picked up by mistake! I rushed back to the station (just next door to the Biltmore) and there, at the Pullman Lost & Found was my bag! Love to all
- Memo from Jerry Donohue and William Shand to Supervisory Group RE: Determination of the Parameter for Silver Molybdate, Ag2MoO4. (Marked Feb 1 1946 Rec'd) [Filed under LP Biographical: Academia: Box 1.017, Folder 17.1]
- Memo from William Shand, Jr. to Supervisory Group, Diffraction Investigation RE: responds to previous memo dated 21 Jan 46 and relates information from manuscript. [Filed under LP Biographical: Academia: Box 1.017, Folder 17.1]
- Press Release: “Great Advances in Medicine and Biology to Come From Study of Sizes and Shapes of Molecules; Specific Action of Drugs Explained by Molecular Configuration”, February 1, 1946. [Filed under LP Scrapbooks, 1941-1945: Box #6.004, Folder 4.12]
- Writes cheque to "First Federal Savings and Loan Association," $210.24. [Filed under LP Biographical: Business and Finance, Box 4.018, Folder 18.1]
- Writes cheque to “AL Lindgren to fix Ford” $30.98 [LP Biographical: Business and Financial 4.073, folder 73.4]
- Writes cheque to “Check to Mrs. C. J. Cox for cash to me” $15.00 [LP Biographical: Business and Financial 4.073, folder 73.4]
- Writes cheque to “Mr. Crellin” $80.00 [LP Biographical: Business and Financial 4.073, folder 73.3]
- Entry in Calendar: “Went to Lido Isle with Peter as Chaperone To ok Crellie” [Filed under LP's Daily Calendar of Events, 1946, 1958-1966, 1968-1970, 1973-1979: Box #5.012, Folder 12.1]
- Letter from Dr. Paul Emmett, Mellon Institute, to LP RE: Asks LP to stop by and see him in Pittsburgh if he can while he is East to lecture in Rochester. Mentions his sister sent him a clipping from Oregon where LP is quoted as disclosing the number of bombs the U.S. has. Adds that Dr. Klug mentioned his letter from LP, and goes on to discuss Klug and others at the Institute. Reports he has been on crutches due to foot injury. [Letter from LP to Emmett February 4, 1946] [Filed under LP Correspondence: Box #109.1, file:(Emmett, Paul, 1937-1959, 1977-1982)]
- Note from Allan Maccoll, Sir Wm. Ramsey and Ralph Forbes Labs, University College London, to LP RE: Inquires if LP received the manuscript “The Resonance Energies and Light Absorption of some Heterocyclic Molecules” he sent before leaving Australia. Requests LP read and send comments. [Letters from Maccoll to LP July 17, 1945, March 5, 1946] [Filed under LP Correspondence: Box #246.7, file:(Mellor, David P.)]
- Report of the CIT Executive Committee Conference on February 2, 1946. LP Safe: Drawer 3, Folder 3.019
- Writes cheque to “Check to Mrs. C. J. Cox for cash to me” $15.00 [LP Biographical: Business and Financial 4.073, folder 73.4]
- Entry in Calendar: “Home from Lido Isle. Big rain” [Filed under LP's Daily Calendar of Events, 1946, 1958-1966, 1968-1970, 1973-1979: Box #5.012, Folder 12.1]
- Letter from H.M. Kilgore, Chair, Subcommittee on War Mobilization, U.S. Senate, to LP RE: Thanks him for his letter in support of legislation for funding of scientific research. Sends a summary of the Senate hearings and a description of the new bill. Requests LP send any suggestions. [Filed under LP Correspondence: Box #200.11, file:(K: Correspondence, 1946)]
- Note from Dr. Thomas Addis to AHP RE: Sends latest protein excretion data pertinent to LP's condition. [Filed under LP Correspondence: Box #2.2, file:(Addis, Thomas 1946-1947)]
- A Bill presented to the 79th Congress, 2nd Session: H.R. For the development and control of atomic energy. Presented by Mrs. Douglas of California, referred to the Committee on Military Affairs. LP Peace: Box 3.017, Folder 17.1
- Letter from LP to AHP. [Filed under LP Safe: Box #1.017, Folder #17.42]
[plain white paper]
Feb. 4 Monday noon
I came up to Rochester on the train last night- and didn't sleep too well, but have spent several hours in bed in the hotel this morning, and also have written my speech. I shall soon have lunch with Leermakers[?], Maury, Albert Noyes, and others, and then go the University. Tonight I shall stay with Maury, and spend tomorrow at Eastman, returning tomorrow night to New York.
Henry took Louie and me to lunch yesterday. He thinks that Feb. 1 would be suitable for arriving at Oxford, and he says that Eastman House is about as good and comfortable a house as there is in Oxford. He introduced me to Fosdick of the Rockefeller Fn, (also to Waldemar Kaempffert), who asked me to see him on Wednesday. Henry suggested that I talk over the whole scheme with Fosdick. (F. & K. were at the Century Club.)
Then I went to a movie, while waiting till train time. "The Imposter", with Jean Gabin- very good. Also the Marx Brothers in "Horsefeathers"- do you remember it? Its really funny. Groucho's song "I'm against it" keeps running through my head. "Whatever it is, I'm against it," "Ever since I commenced it- I'm against it."
This trip is just half over- whoopee!
- Letter from LP to Dr. Milton Silverman. RE: Is sending a glossy print of the Model P Pauling Oxygen Meter so that the photograph might be reproduced in the Summary Technical Report. For Division 11. [Filed under LP Science: Scientific War Work - Materials re: the Pauling Oxygen Meter, 1940-1947: Box #13.001 Folder #1.2]
- Letter from Prof. Charles C. Smyth, Department of Chemistry, Princeton University, to LP RE: Requests LP recommend candidates for instructorship positions in chemistry for the next fall. [Letter from LP to Smyth February 25, 1946] [Filed under LP Correspondence: Box #163.1, file:(Hughes, Edward)]
- Program: First Harrison Howe Memorial Lecture, Rochester (N. Y.) Section, American Chemical Society, February 4, 1946. [Filed under LP Scrapbooks, 1941-1945: Box #6.004, Folder 4.12]
- Transcript, Program: Analogies Between Antibodies and Simpler Chemical Substances, First Harrison Howe Memorial Lecture, Rochester Section, American Chemical Society, Rochester, New York. [LP Speeches, 1946s.2]
Analogies between Antibodies and Simpler Chemical Substances
By Linus Pauling, Director, Gates and Crellin Laboratories,
California Institute of Technology, Pasadena, CA
Inaugural Harrison Howe Lecture
February 4, 1946
Let me express my deep appreciation of the honor of presenting the first Harrison Howe Memorial Lecture, and my thanks to you for selecting me. I am sure that Harrison Howe, with his broad interests, covering the whole of chemistry and technology, would not consider out of place the subject I have chosen: "Analogies between Antibodies and Simpler Chemical Substances".
I became interested in antibodies ten years ago. Dr. Karl Landsteiner asked me to come to his laboratory at the Rockefeller Institute for Medical Research - he knew that I had been working on the magnetic properties and structure of hemoglobin, and that I was interested in the great general problem of the structure of proteins - and when I went to see him he asked me many questions about the possible interpretation of serological phenomena in terms of the detailed structure of molecules.
Having little knowledge of serology, I found it necessary to ask him many questions before I could attempt to answer his, and he was good enough to permit me to spend a day with him on each of several later trips which I made to New York. Then, in December of 1937, when I was at Cornell as George Fisher Baker Lecturer in Chemistry, he came to Ithaca for a visit of several days, which we devoted to the intensive and critical discussion of immunological experiments and their interpretation.
This was a great experience for me - to have this field of knowledge presented and clarified to me by its great Master, the man who had contributed more to it and had thought more deeply about it than any other living being; and I have a deep feeling of gratitude to him for his kindness and interest. Dr. Landsteiner (as well as Professor Michael Heidelberger) encouraged me in 1940 to publish my first paper on the structure of antibodies and to begin experimental work in this field; and he followed the course of the work, carried on in Pasadena in collaboration with Dan H. Campbell, David Pressman, and several graduate students, and with the support of The Rockefeller Foundation, until his death in 1943.
Antibodies as Chemical Substances
Chemists are not accustomed to thinking of antibodies as chemical substances, nor of the serological reactions shown by antibodies as chemical reactions. It is true that antibodies, containing tens of thousands of atoms in each molecule, are far more complex than simple chemical substances with around 10 or 20 atoms per molecule; and some immunological reactions, such as the anaphylactic shock shown by a previously sensitized animal when it receives a small injection of the antigenic substance to which it is sensitive, do not have much in common with chemical reactions. Nevertheless, a comparison of antibodies with simple chemical substances and of serological reactions with ordinary chemical reactions provides a basis for understanding antibodies and their behavior, and also suggests new experiments to be carried out.
When an antigen (a substance, usually a protein, foreign to the animal) is injected into an animal, it may cause the production, in the blood stream and cells of the animal, of substances which are related in their properties to the antigen which was injected.
Antibodies are proteins (serum globulin), with very large molecules, the molecular weight being often 160,000 and sometimes as great as 1,000,000. A striking property possessed by most antibodies and antitoxins is that of forming a precipitate with the corresponding antigen. For example, when an animal is injected with egg albumin, antibodies homologous to the egg albumin are formed, and the serum of the animal gives a precipitate when it is mixed with a solution of egg albumin, the precipitate containing both antibody and egg albumin.
A most striking property of antibodies is their specificity - the serum homologous to egg albumin may give a very large precipitate when mixed with a solution of egg albumin, and give no precipitate at all when mixed with a solution of any other protein. There are some exceptions to this specificity: An antiserum homologous to hen egg albumin will give a precipitate with duck egg albumin, but the quantity of the precipitate will be smaller than that formed with hen egg albumin. This specificity is almost limitless in extent. It was shown by Landsteiner that antisera can be produced which react with different chemical groupings attached artificially to proteins, and these chemical groups can be synthesized in number almost without limit.
After several decades during which the nature of serological precipitation was in doubt, it has now been shown by convincing experiments that a serological precipitate is a framework of antigen and antibody molecules, with molecules of both antigen and antibody in the framework attached to their neighbors by two or more bonds. The molecules of antigen and of antibody are thus to be considered as having a valence (analogous to, but not identical with, ordinary chemical valence) equal to or greater than 2.
There is some evidence that in most antisera many of the antibody molecules have two combining regions - that is, they are bivalent. Some antisera seem to contain univalent antibodies, capable of combining with antigen molecules, but not of forming a precipitate with them. The mechanism of the formation of a serological precipitate is the following: Each antigen molecule attaches to itself two antigen molecules, this process continuing until the framework of molecules reaches a macroscopic size, constituting a precipitate. Many of the ordinary precipitates that the chemist meets in his work are formed in the same way. An example is the precipitate of silver cyanide produced when a solution of a silver salt is mixed with a solution containing cyanide ion. The silver ion has the property of forming two covalent bonds with cyanide ion; it attaches to itself two cyanide ions, which stick out on either side of it. The cyanide ion also has the property of forming two covalent bonds, one formed by the carbon atom and one by the nitrogen atom. In this way long chains of alternating bicovalent silver and bicovalent cyanide groups are formed, and ultimately these long chains arrange themselves side-by-side to form the silver cyanide precipitate.
A similar process is involved in the precipitation of Prussian blue when a solution containing ferrous ion is mixed with a solution containing ferricyanide ion. The ferricyanide ion contains six groups attached to a central ferric atom. Each of these six groups is capable of attaching itself to a ferrous ion, and the ferrous ion can form bonds with six cyanide groups. This process leads to the formation of a cubical framework extending through space, the framework of the Prussian blue precipitate.
Specificity of Antibodies
The second property of antibodies which has an analog in the chemistry of simple substances is the great specificity of interaction of antibody and the homologous antigen. It has been shown that this specificity is due to a striking complementariness in structure between a portion of the surface of the antigen molecule and a combining region on the antibody. After the antigen is injected into the animal, antibody molecules are synthesized by the animal in such a way that a region (two regions for a bivalent antibody) of the antibody assumes a configuration which mirrors a portion of the surface of the antigen molecule. This complementariness in structure leads to a strong attraction between the antibody molecule and the antigen, because it permits this combining region of the antibody molecule to get into close contact with the antigen molecule; the closer that the two molecules can get in contact with one another, the stronger the intermolecular forces of attraction between them.
A protein molecule serving as an antigen usually has a rather complicated surface structure, and it is easy to see how the great specificity shown by antibodies arises. The reaction shown by simple chemical substances which is analogous to that of specific combination of antigen and antibody is the formation of a crystal of a substance from solution. A crystal of a molecular substance is stable because all of the molecules pile themselves into such a configuration that each molecule is surrounded as closely as possible by other molecules - that is, if a molecule were to be removed from the interior of a crystal, the cavity that it would have very nearly the shape of the molecule itself. We can say that the part of a crystal other than a given molecule is very closely complementary to that molecule. Other molecules, with different shape and structure, would not fit into this cavity nearly so well, and in consequence other molecules in general would not be incorporated in a growing crystal. This is the explanation of the astounding chemical process of purification by crystallization - from a very complicated system, such as, for example, grape jelly, containing hundreds of different kinds of molecules, crystals which are nearly chemically pure may be formed, such as crystals of cream of tartar, potassium hydrogen tartrate.
Deviation from specificity occurs in serological reaction when an antiserum combines with an antigen other than the immunizing antigen, and it occurs in crystallization when solid solutions are formed. There are striking similarities between these two kinds of deviation. For example, the antibody to an azoprotein containing azobenzoic acid with a bromine atom in the meta position shows strong precipitation with an azoprotein containing azobenzoic acid with a methyl group in the meta position; this complete cross reaction is the result of the fact that the bromine atom and the methyl group have very nearly the same shape and size, although their chemical properties otherwise are quite different. Similarly, solid solutions are formed by corresponding bromine-substituted and methyl-substituted benzenes.
I could give many more examples in illustrating my thesis, but I shall refrain, remembering the observation by Voltaire that "the secret of being a bore is to tell everything".
Potentialities of the Theory in Other Fields
Although crystallization is the only simple chemical reaction which shows striking similarity to serological reactions with respect to specificity, there are many physiological phenomena which are similarly specific, and for which the specificity can be given a similar explanation. The specificity of the catalytic activity of enzymes is due to a surface configuration of the enzyme such as to make the enzyme complementary to the substrate molecule, or, rather, to the substrate molecule in the strained state that occurs during the catalytic reaction.
The specific action of drugs and bactericidal substances has a similar explanation. Even the senses of taste and odor are based upon molecular configuration rather than upon ordinary chemical properties - a molecule which has the same shape as a camphor molecule will smell like camphor even though it may be quite unrelated to camphor chemically.
I am convinced that it will be found in the future, as our understanding of physiological phenomena becomes deeper, that the shapes and sizes of molecules are of just as great significance in determining their physiological behavior as are their internal structure and ordinary chemical properties. I believe that the thorough investigation of the shapes and sizes of molecules will lead to great advances in fundamental biology and medicine; and because of this belief I am now turning my efforts in this direction. It seems clear that complementariness of the sort we have been considering must be involved in the autocatalytic activity (production of replicas) and heterocatalytic activity (production of other specific molecules) of the tens of thousands of genes that carry to us our inheritance from our ancestors.
And, moreover, I am convinced that progress in our attack against disease, in our better understanding of the human body, of bacteria, viruses, and other vectors of disease, and of their interactions with each other depends on a better understanding of intermolecular forces and interactions. "The long habit of living indisposeth us to dying"; and, as we have got better and better control over the infectious diseases, the degenerative diseases - cancer, cardiovascular disease - have become more and more important, and call more and more urgently for control: but we cannot yet attack these diseases in a straightforward way - we need leads, hints, which a better understanding of the phenomena of growth, development, and disease in terms of molecular structure would surely provide. I have hopes that it will be possible to carry on a program of research in molecular structure that will lead to significant contributions to biology and medicine.
Nearly sixty years ago Walt Whitman wrote about Life and Death:
The two old, simple problems ever intertwined,
Close home, elusive, present, baffled, grappled,
By each successive age insoluble, passed on,
To ours today - and we pass on the same.
Let us resolve that as we pass on these problems to our fellow generation we shall make also our contribution toward their solution.
- Writes cheque to "William W. Taylor Jr. Co.," $5.07. [Filed under LP Biographical: Business and Finance, Box 4.018, Folder 18.1]
- Writes cheque to “S. Pacific. Tickets to Berkeley” $57.83 [LP Biographical: Business and Financial 4.073, folder 73.4]
- Letter from John S. Snyder, John Wiley and Sons, Inc., to LP . RE: Snyder is pleased to hear that LP has hope for finishing his manuscript, and looks forward to hearing about any developments regarding it. He thanks LP for his comments regarding Pressman. [Filed under LP Manuscripts of Books, 1947b5.22]
- Letter from LP's secretary to Dean Webster G. Simon, Western Reserve University, RE: Writes that his letter has been received, and that LP will respond when he returns to the office in a few weeks. [Letters from Simon to LP January 30, 1946, from LP to Simon February 19, 1946] [Filed under LP Correspondence: Box #165.11, file:(H: Correspondence, 1946)]
- Letter from the Secretary to LP, to Mr. Sherman S. Shaffer, Humble Oil and Refining Co., Technical and Research Div., RE: States that LP will be gone for some time, and suggests Shaffer direct his question to Dr. Harold D. Springall, the coauthor of LP for the article in question. [Letter from H. H. Meier to LP January 24, 1946] [Filed under LP Correspondence: (S: Correspondence, 1946), #377.16]
- Newspaper Clipping: “Shapes of Molecules Provide new Approach to Biology”, Pasadena (California) Star-News, February 5, 1946. [Filed under LP Scrapbooks, 1941-1945: Box #6.004, Folder 4.12]
- Writes cheque to “Adohr Milk” $14.80 [LP Biographical: Business and Financial 4.073, folder 73.4]
- Writes cheque to “Athenaeum” $19.89 [LP Biographical: Business and Financial 4.073, folder 73.4]
- Writes cheque to “Coach Van Lines Inc. Check for Taka - He gave me cash” $3.10 [LP Biographical: Business and Financial 4.073, folder 73.4]
- Writes cheque to “LA Times to March 1" $3.90 [LP Biographical: Business and Financial 4.073, folder 73.4]
- Writes cheque to “P. Star News to Feb 1" $2.25 [LP Biographical: Business and Financial 4.073, folder 73.4]
- Writes cheque to “Roy Edwards” $7.69 [LP Biographical: Business and Financial 4.073, folder 73.4]
- Writes cheque to “S. Counties Gas. Two months service” $23.27 [LP Biographical: Business and Financial 4.073, folder 73.4]
- Writes cheque to “Union Oil Co” $5.18 [LP Biographical: Business and Financial 4.073, folder 73.4]
- Writes cheque to “Wm. Taylor. Sweater for Crellie” $5.09 [LP Biographical: Business and Financial 4.073, folder 73.4]
- Entry in Calendar: “Women's Club” [Filed under LP's Daily Calendar of Events, 1946, 1958-1966, 1968-1970, 1973-1979: Box #5.012, Folder 12.1]
- Letter from George Pepper to LP. Encloses proposed statement of policy of the Science and Education Division of the Hollywood Independent Citizens Committee of the Arts, Sciences and Professions. Suggests that this statement be the basis of discussion at the February meeting of the coordinating committee. LP Peace: Box 4.012, Folder 12.7
- Letter from LP to AHP. [Filed under LP Safe: Box #1.017, Folder #17.43]
Wednesday night, 10 PM
I've been very busy since I last wrote. I arrived in Rochester at 6AM, had breakfast, got a room in the hotel, and rested in bed & worked on my speech till 12.45, had lunch with some of the men, and went to the University with Albert. Then came the dinner ([[puuk]), a long boring talk on Harrison Howe by Murphy, and my talk (I mentioned Voltaire's remark "The secret of beig a bore is to tell everything"). There were about 500 people there, and they were unbelievably enthusiastic. I stayed overnight with Maury and Dorothy, and spent Tuesday at the E.K. labs, and Distillation Products (Hickman), taking the night train to New York, This morning I saw Henry, and then went to the Rockfeller Fn. Weaver had his operation Friday, and got along well. He may be back on the job in a couple of months. Fosdick said the R.F. would do part but not all of our job, Then I saw Heffron and Wickman of the Commonwealth Fn- I talked about our plans, but haven't yet asked if they would put up some of the money. Tomorrow I am to see the Natl Found. For Infantile Paralysis.
I had lunch with Miller of the RF, and later saw Dr Willard, Editor of Chem Monographs. It was a tiring day, and my nose began to run, so I came to the hotel, and used Thizodrine, and stayed in bed all evening. Perhaps it won't develop- it isn't bad.
It's fine that Liny is a sergeant.
Love to all from
- Note from Frank Aydelotte to LP RE: Expresses his hope that LP will take the position at Oxford. Asks him to send any correspondence regarding the matter to his secretary at Princeton. Goes on to inform him that he has been recently ill. (Note in pencil at top margin: “File with other Eastman Prof. correspondence”) [Letters from LP to Aydelotte January 23, 1946, February 28, 1946] [Filed under LP Correspondence: Box #6.21, file:(Aydelotte, Frank, 1940-1956) and copy in #299.8 (Oxford University, [re: Eastman professorship and residency in Oxford] 1946-1948)]
- Letter from A. J. Dempster, J. Franck, William D. Harkins, R. S. Mulliken, H. C. Urey, and Sewall wright, to Members of the National Academy of Sciences. RE: Informs them the McMahon bill and its purpose. Encloses two cards to be returned if they agree with their stance. [Filed under LP Science: National Academy of Sciences, 1945-1951: Box #14.019 Folder #19.2]
- Letter from E. K.. Wickman to LP. Provides LP with figures concerning the National Foundation for Infantile Paralysis and its assets. LP Safe: Drawer 3, Folder 3.019
- Entry in Calendar: “Peter, Linda movie” [Filed under LP's Daily Calendar of Events, 1946, 1958-1966, 1968-1970, 1973-1979: Box #5.012, Folder 12.1]
- Letter from Dan H. Campbell, CIT, to E. C. Hay Company. RE: Sends information regarding a modified gelatin. Describes oxypolygelatin. [Filed under LP Science: Assorted LP War Work, 1940-1946: Box #13.006 Folder #6.1]
- Letter from Harris M. Chadwell to LP. Informs LP that he thinks another organization will create a small group of consultants to continue the program formerly under Section 19.1 and that he hopes LP will give the matter consideration if he is approached in connection to this matter. LP Safe: Drawer 2, Folder 2.010
- Minutes of the meeting of the Executive Committee, Pacific Division, AAAS. [Filed under LP Science: American Association for Advancement of Science, 1938-1964: Box #14.001 Folder #1.3]
- Note from Dr. Thomas Addis to AHP RE: Encloses an x-ray request form and details for the Paulings' next visit to the lab. Also mentions that allow he does not understand what is causing the proteinuria fluctuations, at this small level they do not worry him. [Filed under LP Correspondence: Box #2.2, file:(Addis, Thomas 1946-1947)]
- Theory of Resonance. Jackson Laboratory Lecture Series, Lecture no. 6. Wilmington, DE: E. I. Dupont de Nemours & Co. (February 8, 1946): 1-13. Written by: LP. [Filed under: LP Publications, 1946p.4]
- Typescript, Correspondence: Theory of Resonance, Jackson Laboratory Lecture Series, Du Pont, Inc., Wilmington, Delaware. [Filed under: LP Speeches, 1946s.3]
- Entry in Calendar: “Crellin went to Beach. Folk Dancing. Mr. Babcock Called. Elmer C. Ball Ur. in therapeutics call middle of week again.” [Filed under LP's Daily Calendar of Events, 1946, 1958-1966, 1968-1970, 1973-1979: Box #5.012, Folder 12.1]
- Report of the CIT Executive Committee Conference on February 9, 1946. LP Safe: Drawer 3, Folder 3.019
- Entry in Calendar: “Peter's Birthday. Concert” [Filed under LP's Daily Calendar of Events, 1946, 1958-1966, 1968-1970, 1973-1979: Box #5.012, Folder 12.1]
- Entry in Calendar: “Paddy” [Filed under LP's Daily Calendar of Events, 1946, 1958-1966, 1968-1970, 1973-1979: Box #5.012, Folder 12.1]
- Letter from D. Aron to Gladys Wilson. RE: Acknowledged receipt of the letter and glossy print. [Filed under LP Science: Scientific War Work - Materials re: the Pauling Oxygen Meter, 1940-1947: Box #13.001 Folder #1.2]
- Memorandum from R.W. Sorensen [approved by S.S. Mackeown and F.W. Maxstadt] to the Executive Committee of the Electrical Engineering Faculty at CIT. Requests for a reconsideration of the present division grouping of courses as it relates to electrical engineering. LP Safe: Drawer 3, Folder 3.019
- Entry in Calendar: “Paddy came home. Chamber of Commerce Dinner for Caltech, 6:45pm” [Filed under LP's Daily Calendar of Events, 1946, 1958-1966, 1968-1970, 1973-1979: Box #5.012, Folder 12.1]
- Letter from Harry Hoijer to LP. Informs that the Continuations Committee of the Science and Education Committee will meet on Monday, February 18th at the HICCASP office. Includes list of subjects for discussion. [Handwritten note: Returned card 2/13/46 - No] LP Peace: Box 4.012, Folder 12.7
- Writes cheque to "Southern Pacific Railroad," $7.25. [Filed under LP Biographical: Business and Finance, Box 4.018, Folder 18.1]
- Letter from LP to Mr. Byck, Shell Development Research Club, RE:
- Letter from Louis Harris, HICCASP, to LP. Asks pardon in delay of answering LP's letter of January 25. Has not written to Prof. Allen as he is already a member of the organization. LP Peace: Box 4.012, Folder 12.7
- Letter from James Henderson, University of London to LP RE: Asks if he would deliver a few lectures chosen by himself as a part of their Special University Lectures series, tells him the dates, ask him for an alternative time if those don't work, tells him of the honorarium, and encloses some notes in regard to the publication of his lectures. (“Notes on the Publication of Special University Lectures” attached to letter] [Letter from LP to Henderson March 20, 1946] [Filed under LP Correspondence: 299.8 [Oxford University, [re: Eastman professorship and residency in Oxford] 1946-1958]
- Typescript: A Proposed Program of Research on the Fundamental Problems of Biology and Medicine [Filed under LP Manuscripts, 1946a.1]
- Writes cheque to "Takaichiro Hatakeyama," $170.00. [Filed under LP Biographical: Business and Finance, Box 4.018, Folder 18.1]
- Confidential meeting minutes of the Executive Committee. Discussed the Texaco Development Project, Shellmar Corporation Contract, appointments, etc. [Filed under LP Biographical: Academia: Box #1.029 file 29.1]
- Entry in Calendar: “Dinner at Sarah's Dancing School afterwards” [Filed under LP's Daily Calendar of Events, 1946, 1958-1966, 1968-1970, 1973-1979: Box #5.012, Folder 12.1]
- Letter from W. H. Rodebush, Dept. of Chemistry, University of Illinois, to LP RE: States they are looking for a physical chemistry instructor for two semesters, with a $2,800 salary, preferably someone interested in x-ray research who could make use of Dr. Clark's equipment and expertise. [Letter from LP to Prof. W. H. Rodebush February 25, 1946] [Filed under LP Correspondence: #335.6]
- U.S. Government Transportation Identification Card. Certifies that LP is an employee of the Department of State engaged on Official business. LP Safe: Drawer 2, Folder 2.006
- Entry in Calendar: “Wedding. P. Hayard- St. Phillips Church till 4pm” [Filed under LP's Daily Calendar of Events, 1946, 1958-1966, 1968-1970, 1973-1979: Box #5.012, Folder 12.1]
- Letter from Elizabeth Darling Gillette to LP. [Filed under LP Biographical: Personal & Family, Family Correspondence: Assorted Pauling/Darling Materials, 1912-1994: Box #5.054, Folder 54.12]
1 Feb. 16th 1946
E.3628 - 5th Ave.
Was so glad to get you letter. Am writing you between your two trips East. Thank you for writing and thanks too for you invitation to visit you. How glad I would be to do so. Maybe I can. I have never been in Calif. but most of all I would like to see you. Jan. 29th I was 84 years young. I can't realize it. I feel so young. I can still run for the bus, and can work all day.
The Darling family were born in Collingwood
Canada and our parents moved to Lewiston, N.Y. five miles from Niagra Falls when I was a baby. We lost our parents when I was two years old. There were six of us. John, Linus, Will, Mary, Addie and myself. I was adopted (not legally) into a family by the name of Robertson who lived seven miles from Lewiston. Mary went to live with a family by the name of Gray. Addie was take back to Canada by some of our relatives and I never saw her again. The boys were scattered. Linus told me he lived in different homes till he found one where he could go to school.
He must have been not far from me as I remember of his coming to see me when I was a little child. John went back to Canada. Will went to Michigan where he married and Linus drifted out to Oregon. We corresponded for years before he married. What a tragedy for a family to be so separated. I was the lucky one of the family as I had a better home than the others. Though Mother love was lacking. I missed it without knowing what I missed.
Except the one visit from Linus I never saw
any of them till Mary was eighteen and I twelve and she came to see me. I had driven with the folks past her home dozens of times without knowing that my sister lived there. She went by her own name but I went by my adopted name. Will had two children - Weldon who grew to manhood then was killed in an auto accident, and Gussie who is married and I think lives near Portland. Will visited me here a few years ago and died soon after.
Linus' second wife Lucy was the step mother of his
girls and was kind and motherly. He afterward married Adaline and they lived in Portland where he had a law office. I visited them there and I was in Condon when he and Lucy lived on her ranch. John and I corresponded for years. He was captain on a lake steamer. Soon after I first saw Mary she went out to work for a Gilette family. L.P. Gillette who lived on the Niagra River road and in after years became my uncle by marriage. I was her brides maid and best man was the young man who afterward
became my cousin by marriage. That sounds like a novel does'nt [sic] it? Wedding was in the L.P. Gillette home. How little I thought what the after years would bring me. I was proud of Linus because he was self made - no one to do anything for him yet he because a lawyer. I am the last of the family. the rest have all passed on. Three years previous to my marriage I clerked in a big department store in Youngstown, five miles from my home on the bank of Niagra River. Just across was Canada
I have a son Harold who is now fifty - a bachelor and lives with me, and a daughter Helen married and living in Spokane. They have a son in second year of High school. Helen works in an office for the city. She need some help at home so I go there two days a week. It helps her out and helps me financially. I get State pension but made my living at sales work till five years ago. I worked for the Avon Co. fifteen years. That is a cosmetic Co. Before that I was city sales lady for a
syrup Co. with them two years. Part of that time I worked other towns for them. Was gone once three weeks. At the end of two years I gave out and had to quit. A hard thing to do. After a short vacation I was quite rested up and took up the Avon Cosmetic work. After fifteen years I was worn out and after a short rest went to help Helen out.
There is or was a Dr. Gillette, a physician in Rome, N.Y I don't see how you could have heard of him unless it was his propagating The Rome Beauty apples. You might
have heard of Clerance [sic] Gillette. He was with a college in Fort Collins, Colorado and had several abbreviations before his name. His sister visited us here two years ago. She lives in Eugene, Oregon. She was a friend indeed to one when we lived in Klamath County. She lived there too. Thanks for telling me of the girls. I did'nt [sic] know till then that you had lost your parents. In one of the articles I clipped from my paper you were called Dr. and in the other one Professor. Are you both and of what? Please tell
me what your work is.
I am really quite proud of you. Your picture was with one of them too.
Well really I think it's time to quit. Hope you are not tired of this long letter. I have written on both sides of paper as I had so much to say.
Hope to see you some day.
Thank you again for writing.
- Entry in Calendar: “To San Francisco - The ‘Lark'” [Filed under LP's Daily Calendar of Events, 1946, 1958-1966, 1968-1970, 1973-1979: Box #5.012, Folder 12.1]
- Writes cheque to “Mira Loma H2O” $6.15 [LP Biographical: Business and Financial 4.073, folder 73.4]
- Writes cheque to “T. W. Mather. Clothes for me” $253.45 [LP Biographical: Business and Financial 4.073, folder 73.4]
- Letter from Catherine Schlegelmilch, College Department, The Macmillan Company to LP RE: Tells him that Mr. Freeman was in the office with just enough time to open LP's package, but didn't have enough time to write before having to rush out of town again, explains that he will be back later this week and will write LP then. [Letter from Freeman to LP February 21, 1946] [Filed under LP Correspondence: 439.4]
- Manuscript, Correspondence: Bonds Between Metal Atoms in Metallic and Non-Metallic Substances, Shell Development Research Club, Sigma Xi Lecture, Berkeley, California. [Filed under: LP Speeches, 1946s.4]
Shell Development Sigma Xi Club Lecture, Berkeley, Feb. 18, 1948
"Bonds between Metal Atoms in Metallic and Non-metallic Substances."
My chairman, ladies and gentlemen. I am not talking about antibodies today, not because I have tired of them, but because I can't repeat my talk here of a year ago. But metals are interesting - and we don't understand them very well yet.
A year ago I mentioned Crellin and his interest in the days in September. Last year he had two teeth extracted - .
To get back to metals - every once in a while a theoretical physicist says something that turns my stomach. This happened a few years ago about metals. Mott and Jones said that in nickel there is a 0.61 bonding electron per atom, and in iron 0.22! This is silly - when we compare tensile strength, etc. of Ni and Fe with K, say, which has 1; or with silk fibers with one covalent bond per string to be broken - there are 12 contacts, and hence there must be ~ 6, say, bonds per iron atom!
Why did Mott and Jones say this? They think of 3d and 4s orbitals as much different. μ = 0.61 for Ni, 0.22 for Fe. But we must hybridize 3d, 4s, and 4p. This would permit 9 resonating bonds for Co. Actually there are ~6 from Cr to Cu. Explanation.
We might ask - since this metal-metal bonds are good bonds, would they not occur in non-metallic compounds? This is an interesting question - there are many interesting questions such as the explanation of the astounding specificity of serological reactions. You remember that here the cause is structural complementariness of antigen and antibody. Is there any analogy among simpler chemical substances? There is a striking one - I don't believe I mentioned it a year and a half ago - I hadn't yet thought of it. It is crystallization.... And there are occasional isolated instances of surprising specificity in inorganic and organic chemistry. For example, tungsten as W +++ occurs only as W2Cl9
--- (also W2Cl29
--). Why not WCl6
---? Why not W2F9
---? Answer - configuration permits a W-W bond, in addition to the W-Cl bonds.
Are there any other examples? I asked a young man that - UC Ph.D. - and he couldn't think of any. I then said "Have you ever heard of calomel?"
Cl-Hg-Hg-Cl Also Fe2(CO)9 diferricdihydroxytetraphenanthroline. Ag2F, Pb94-, Ta6Br12
--, sulvanite, Mo3Cl4
--, MoS2 - molybdenite, like graphite.
What about hydrolysis of Fe(H2O)6
+++? Can yellow color be due to polymers? Limonite yellow. Lepidocrocite and Goethite red, also FeOCl. Hematite red-black. Also Cu(OH)2 blue -> CuO black.
This brings me to a matter that has long interested me - effect on color of having an element in two valence states. Fe(OH)2 white -> green black -> Fe(OH)3 red brown.
CuCl and SbCl3 colorless -> brown black -> CuCl2 and SbCl5 blue.
Cs2AuAuCl6, Biotite, Mica -> Russian blue; magnetite, tourmaline, Fe++, Fe+++, iluvaite, all black.
But why go on? Voltaire said "The secret of being a bore is to tell everything." It is clear that there is much here that we do not understand - perhaps that is its attraction. Thomas Wright in 1601 said "Nothing is so curious and thirsty after knowledge of dark and obscure matters as the nature of man." So let us continue to think about these questions - to look for uniformities among facts that at first seem disconnected - and in this way do our bit in obtaining an understanding of the great and complex and terrifying world about us.
- Memo outlining Immediate Engineering Division Needs. [Filed under LP Biographical: Academia, California Institute of Technology: Assorted Financial Materials: 1945-1965: Box #1.032, Folder 32.1]
- Entry in Calendar: “Return from Frisco” [Filed under LP's Daily Calendar of Events, 1946, 1958-1966, 1968-1970, 1973-1979: Box #5.012, Folder 12.1]
- Letter from A. V. Grosse, Secretary, to Beilstein-Gmelin Committee. RE: Informs them that Seaborg, and LP have joined the committee. Suggests meeting before adding any other members. Encloses a letter from Roger Adams. [Filed under LP Science: American Chemical Society: Materials re: Committees and Awards, 1938-1950: Box #14.008 Folder #8.3]
- Letter from LP to Dean Webster G. Simon, Western Reserve University, RE: Apologizes for the delay in response due to an eastern trip. Sends his opinions concerning Dr. Bruce Hicks as requested. [Letter from LP's secretary to Simon February 5, 1946] [Filed under LP Correspondence: Box #165.11, file:(H: Correspondence, 1946)]
- X-ray report performed on LP's chest by Dr. Edward Leef. Notes that heart and aorta are not enlarged and that there is no sign of disease in the lungs. [Filed under LP Correspondence: Box #2.2, file:(Addis, Thomas 1946-1947)]
- Entry in Calendar: “Arrive home. Paddy still has a bit of cold” [Filed under LP's Daily Calendar of Events, 1946, 1958-1966, 1968-1970, 1973-1979: Box #5.012, Folder 12.1]
- Letter from Frieda F. Halpern, Division Director, ICCASP, to LP. Asks LP to discuss matter of a medical advisory council for the Hollywood ICC with Dr. Frazier MacDonald and forward the names of West Coast physicians who could serve on such a council. [Reply from LP, March 16, 1946]. LP Peace: Box 4.012, Folder 12.7
- Letter from John A. Behnke, W.B. Saunders Company, to LP . RE: Behnke wonders if LP is coming east for the American Chemical Society meeting, and if so would like to meet with him to discuss LP's general chemistry text. [Filed under LP Manuscripts of Books, 1947b5.17]
- Chemistry 1a Final Examination. Three hours, ten questions, ten points each. [Filed under LP Biographical: Academia: Box 1.013, File 13.12]
- Entry in Calendar: “Tea Athenaeum 4 to 6 serve punch” [Filed under LP's Daily Calendar of Events, 1946, 1958-1966, 1968-1970, 1973-1979: Box #5.012, Folder 12.1]
- Letter from E.T. Anderson, Department of State, to LP. Informs LP that Mr. Eaton feels that March 15th would be a better date for Dr. Lothrop and that Mr. Richter has already agreed to that date. [Letter from LP to the Secretary of State, February 25, 191946] LP Safe: Drawer 2, Folder 2.010
- Letter from William H. Freeman, Jr., College Department, The Macmillan Company to LP RE: Explains why he could not answer sooner, tells how he has had the outline forwarded to Mr. Bennet in their New York office, and warns him that all publishers are currently laboring under extreme difficulties in all phases of book manufacture. Adds that he mentioned to Mr. Bennett that LP would not use early publishing as a deciding factor. [Letter from Schlegelmilch to LP February 18, 1946] [Filed under LP Correspondence: 439.4]
- Supplemental report to LP's X-ray of February 19th by Dr. Edward Leef. Reports that as compared with the 1941 films of LP's chest there have been no changes in heart shape or size. [Filed under LP Correspondence: Box #2.2, file:(Addis, Thomas 1946-1947)]
- Writes cheque to "Hollywood Independant Citizen Committee," $10.00. [Filed under LP Biographical: Business and Finance, Box 4.018, Folder 18.1]
- Writes cheque to “F.C. Nash. Shoes” $7.12 [LP Biographical: Business and Financial 4.073, folder 73.4]
- Writes cheque to “HJC Asp McClanahan Recall” $10.00 [LP Biographical: Business and Financial 4.073, folder 73.4]
- Ch 1b Freshman Chemistry Final Examination (Three hours. Pauling's “General Chemistry” may be used.) [Filed under LP Biographical: Academia: Box 1.013, Folder 13.12]
- Entry in Calendar: “Dinner for Houston's Michal Bowen 6:30. Between 2 to 4. (Page Dinner?)” [Filed under LP's Daily Calendar of Events, 1946, 1958-1966, 1968-1970, 1973-1979: Box #5.012, Folder 12.1]
- Minutes to the Meeting of the California Institute of Technology Board of Trustees. [Filed under LP Biographical: Academia, California Institute of Technology: Assorted Financial Materials: 1945-1965: Box #1.032, Folder 32.1]
- Writes cheque to “Aug. Fn. Bringing Books up to date” $47.36 [LP Biographical: Business and Financial 4.073, folder 73.3]
- Letter from Linus Pauling Jr to AHP RE: Talks about time spent with Moe and the Mirsky's. He shipped some boxes home and thinks he will be home by March 10th at the very earliest. [Filed under LP Biographical: Personal & Family, Family Correspondence: Linus Carl Pauling, Jr. 1946-1956: Box #5.037, Folder 37.2]
24 February 1946
Life has been moving along at a fair rate, and I was very happy to get your letters.
I went to see Moe one afternoon, and then had lunch with him. He told me about Dad's
going to England next February and about the Oxford house and the situation. Sounds like a fine
thing. He also talked about being in the navy during World War I, and since he was a first mate
on a transport we had fun discussing the sea and the changes in present day operations.
Mirsky's tell me that Dubjakuski (or however it is spelled) told them that Dad and
Tolman are a sort of governing committee for Caltech. Committee sort of leans toward
chemistry, doesn't it? Anyway, such information through biologists can't be much trusted
through the same channels I'm told that there is some mistrust of Beadle.
Several days ago I shipped some boxes home collect, because I thought that is good way
to insure their delivery. The moving will follow later some 13. The boxes contain some of the
last I've acquired in the last six months.
Now for the news to date: I'm off the ship, and in Fort Hamilton awaiting processing and
orders to proceed to fort McArthur for separation from the grand old army. So if all goes well
I'll be hitch hiking my weary way to Pasadena within two weeks! That's a conservative
estimate, because I should be out of here in three days, but I want to average in stop over in
Indiana for a couple of days if I can. Might just possibly make it home by March 10th the best
possible way I could celebrate coming of age and a new freedom. Makes me pretty happy.
Right now I'm uncomfortable with a bad cold acquired with the move from ship to
barracks. The snow, ice, and freezing weather don't bother me particularly I don't have to stay
outside. The snow is often beautiful.
I'm tremendously happy to learn about Pete's being president of the frosh class. A fine
achievement. Give him my congratulations and best wishes. I'll be glad to get home and see the
growth of the family it's been a good half-year.
All my love,
- Letter from Linus Pauling Jr to LP RE: Says he got off the ship which was a surprise as he only has 29 months of service. He will be at Fort Hamilton but expects to be on the way to Fort McArther soon. He received a letter from Berkeley saying he could be readmitted upon approval of the dean. Talks about possibly going to summer school. Wishes Linus a Happy Birthday. [Filed under LP Biographical: Personal & Family, Family Correspondence: Linus Carl Pauling, Jr. 1946-1956: Box #5.037, Folder 37.2]
24 February 1946
This hasn't happened for a long time I'm caught without ink. Poor form to write in
pencil, especially since I write so seldom anyway, but I hope you'll forgive me.
I've been existing in a sort of vacuum for the last four or five days, since I found out that
I could be taken off the ship for discharge. It was a surprise , you see, because I have only 29
months service, and the very lowest authorized time is thirty months. Also I hadn't realized that
I has so much time. I left the ship even though a lot of pressure was put on me to stay. I want to
get adjusted to normal life as soon as possible; also, there is some chance that radar mechanics
will be part of the essential list, and that would slow me up badly.
Now I've been at Fort Hamilton four days, but with the holiday and the weekend, as
orders have come out. But I expect to be on the way to Fort McArther by the middle of next
I wrote to Berkeley before leaving Europe in January, and received a letter enclosing
application forms and saying I could be readmitted (according to my records) upon approval of
the dean, So I shall submit the application as soon as I acquire an official record of my army tech
school carrer [sic].
I'm too late for the spring term, and if I go to England with you in February. I'll have a
hard time squeezing the fall semester in since it ends in late in February. That makes thing
rather simple. I want to get as much time in as possible by going to PCS now perhaps, and to
Although this teller talks principally of my troubles, it is meant to be a birthday greeting
to you. So best wishes Pop, for the coming year, and Happy Birthday!
My love to you
- Entry in Calendar: “Huntington Library 3pm” [Filed under LP's Daily Calendar of Events, 1946, 1958-1966, 1968-1970, 1973-1979: Box #5.012, Folder 12.1]
- Letter from B.H. Sage to LP. RE: Sage has enclosed drawings of the general layout of the Grant School property and the arrangement of the buildings. He believes these structures would be useful to the chemical engineering laboratory during the next few years, until permanent facilities can be provided. [Filed under LP Biographical: Academia, Box 1.020, Folder 20.4]
- Letter from LP to Dr. H. F. Jordan, Assistance Manager, General Laboratories, U.S. Rubber Co., RE: Thanks Jordan for the letter about Mr. Marvin Brooks and states he's given it to Prof. Niemann. [Letter from H. F. Jordan to LP January 25, 1946] [Filed under LP Correspondence: #421.7]
- Letter from LP to Dr. Paul Emmett. [Letter from Emmett to LP February 2, 1946] [Filed under LP Correspondence: Box #109.1, file:(Emmett, Paul, 1937-1959, 1977-1982)]
February 25, 1946
Dr. Paul H. Emmett
115 Yorkshire Road
I was pleased to receive your letter, which came while I was on my trip East. I did not plan to stop in Pittsburgh, and, now that my work with the Explosives Division of the NDRC is over, and that they have closed up the Central Explosives laboratory at Bruceton, it is unlikely that I shall be stopping there in the near future. I was sorry to find you away from town the only times when I came through and tried to get in touch with you.
I am very glad that your work is getting along well. I hope that you will be making a western trip some time, and will stop in to see us.
We are all well. Young Linus is still in the Army - he is on a transport, going back and forth across the Atlantic, and he has even made one trip to India. He should be out of the Army before very long. Peter is in the junior year of high school, and is getting along well - he is the President of his class at Pasadena Junior College.
I was, as you might suspect, misquoted on the atomic bomb matter - some rough estimates that I was making got misinterpreted by the press representative, and spread all over the country. The General didn't think that it was very funny. You probably know that I have never had any connection with the atomic bomb project - I am just an outsider, relatively free to make guesses.
With best regards, I am
- Letter from LP to Dr. Ray Q. Brewster, Chairman, Department of Chemistry, University of Kansas (Lawrence), RE: Recommends to him Dr. E.W. Hughes for the instructorship position in chemistry. Notes that Hughes is leaving his current position at Shell Development Company in Emeryville due to allergy problems, and is searching for a permanent appointment in a more hospitable climate. [Letter from Brewster to LP January 31, 1946] [Filed under LP Correspondence: Box #163.1, file:(Hughes, Edward)]
- Letter from LP to Prof. Charles P. Smyth, Department of Chemistry, Princeton University, RE: Recommends to him Dr. E. W. Hughes, currently at the Shell Development Company in Emeryville, for an assistant professorship or instructorship in chemistry. Notes that he has decided to leave his current position due to allergy problems which have plagued him in that climate. Adds that he is searching for a permanent academic appointment. Suggests Dr. John W. Sease might be an acceptable candidate for an instructorship in organic chemistry. [Letter from Smyth to LP February 4, 1946] [Filed under LP Correspondence: Box #163.1, file:(Hughes, Edward)]
- Letter from LP to Prof. W. H. Rodebush, Dept. of Chemistry, University of Illinois, RE: States that they have no recent graduates for the position, but recommends Dr. E. W. Hughes and discusses his relevant education and experience. [Letter from W. H. Rodebush to LP February 15, 1946] [Filed under LP Correspondence: #335.6]
- Letter from LP to the Secretary of State of the Department of State. Regrets that he won't be able to attend the March 15th meeting. [Letter from Anderson to LP, 2- 21-1946] LP Safe: Drawer 2, Folder 2.010
- Letter from Linus Pauling Jr to AHP RE: Says he will be in Fort Hamilton until he has his 30th month required to leave. Discusses plans for coming days, mentions that Brooklyn Army Base is processing men with only 29 months. He wants to spend a weekend in Indiana with Reba II. A cold he caught has contributed to his depression. [Filed under LP Biographical: Personal & Family, Family Correspondence: Linus Carl Pauling, Jr. 1946-1956: Box #5.037, Folder 37.2]
25 February 1946
Today the bubble is punctured the Fort Hamilton processing section refused to let me
go through because I have only 29 month one less than required. Fort Ham will keep me until
March 27th when I become eligible or until the service time requirements go down. So now I
have a 15 day furlough in any pocket which puts me in the quandary or I can hang around Indiana
or any other place for that matter, I think I'll try ATC if my attempts at discharge fail. The
advantage of that is that I spend less money. I'm actually afraid to walk around N.Y. because I
can't keel the shekel from flowing out of my pocket.
I think the best place for write one is care of Reba Mirsky, 1 W. 68th St. N.Y. I'll keep in
communication with her more after than I'll be of deciding where to go. This afternoon I
discovered one thing more Brooklyn Army Base is processing men with only 29 moths. Therefore tomorrow morning I head for Brooklyn to see if I can't work some deal. I'm pretty
One thing I want to do is spend a weekend in Indiana with Reba II, that leaves a week or
more free I can forge a priority form and try to make it to California via ATC or I can hang
around N.Y. at the fort. But don't say anything personal in the letter. I may ask her to read it to
me over the phone.
Another factor of my depression is the cold that I caught the night of leaving the ship,
and which keeps me form feeling energetic. Bad luck is dogging me.
I'll write tomorrow to inform you of any doings.
All my love,
- Letter from M.H. Arveson to LP RE: Informs LP that the jury has selected him as the recipient of the 35th Willard Gibbs Medal Award. Asks LP to write back confirming his acceptance. [Filed under: LP Speeches, 1946s.8]
- Letter from W.N. Lacey and B.H. Sage to LP, RE: A continuation of an earlier discussion of the Executive Committee, regarding the Texaco Project. [Filed under LP Biographical: Academia, Box 1.020, Folder 20.4]
- Magazine Article: “Rochester Section Inaugurates Harrison E. How Lectures”, Chemical and Engineering News, Vol. 24, No. 4, February 25, 1946. [Filed under LP Scrapbooks, 1941-1945: Box #6.004, Folder 4.12]
- Minutes to the meeting of the Executive Committee Conference. [Filed under LP Biographical: Academia, California Institute of Technology: Assorted Financial Materials: 1945-1965: Box #1.032, Folder 32.1]
- Note from Dr. Thomas Addis to AHP RE: Encloses the x-ray reports and lab reports from LP's last visit. Mentions that Elesa is ill with the flu. [Filed under LP Correspondence: Box #2.2, file:(Addis, Thomas 1946-1947)]
- Letter from Eugene P. Wigner, Princeton University, to LP RE: Invites LP to one in a series of conferences to celebrate Princeton's bicentennial. Requests LP to introduce and lead discussion on Seaborg's address on “Application of Artificial Radioactive Tracers to Chemistry and Medicine” at the first conference which will be sponsored by the Departments of Astronomy, Chemistry, and Physics. [Letter from LP to E. P. Wigner March 20, 1946] [Filed under LP Correspondence: Box #312.11, file: (P: Correspondence, 1946)]
- Memo from C.C. Lauritsen to LP RE: Informs him that they are referring the letter from Nord to LP. [Letters from Nord to Lauritsen January 21, 1946, from LP to Nord April 13, 1946] [Filed under LP Correspondence: Box #287.13, file:(N: Correspondence, 1946)]
- Letter from Dr. G. H. Clowes, Lilly Research Laboratories, to LP RE: Requests reprints of LP's papers in relation to surface films and cell division and metabolism, as he is now returning to these topics with the end of war work. Invites LP to stay with him when he comes on March 19th to give the lecture at the labs. [Letter from LP to Clowes March 13, 1946] [Filed under LP Correspondence: Box #111.4, file:(Eli Lilly and Company, 1946-1951, 1953-1956, 1964-1968, 1970-1972)]
- Letter from Frieda F. Halpern, Division Director, ICCASP, to LP. Encloses script for a film on the atom bomb. Asks LP to read it and give his opinion. [enclosure absent]. LP Peace: Box 4.012, Folder 12.7
- Letter from LP to Frank Aydelotte RE: Informs him that he would possibly be able to Oxford from January to June of 1947. States that he must remain during the fall to oversee the plan for chemistry and biology at Cal Tech. Goes on to say that he has been denied a leave of absence in 1947 by the Board of Trustees due to their belief that he must be in California during this period to manage this new program. However, expresses that he still hopes to be able to go to England for the last two terms of the year. [Note from Aydelotte to LP February 6, 1946] [Filed under LP Correspondence: Box #6.21, file:(Aydelotte, Frank, 1940-1956) and copy in #299.8 (Oxford University, [re: Eastman professorship and residency in Oxford] 1946-1948)]
- Letter from Linus Pauling Jr to AHP RE: Talks about his difficulty traveling, asks when LP will be east again. He wont be going to California since he should be back in about a month. Expresses disappointment of “floating around the country on his 21st birthday.” [Filed under LP Biographical: Personal & Family, Family Correspondence: Linus Carl Pauling, Jr. 1946-1956: Box #5.037, Folder 37.2]
28 February 1946
I got this far after 13 hours on the road although I stopped overnight in Harrisburg. But
the roads out of Pittsburgh are many and small, so after I'd gotten 20 or so miles out of town and
here standing on one shot for an hour. I quit and turned around. I'll continue to Indianapolis by
rail. Possible next week I'll make it to Chicago.
When does Dad expect to go east again? I'll probably be in N.Y. if he gets there in
March. When I get back I'll call up Moe and find out.
I decided not to go to California too much trouble since I'll be out in a month. But I'll
be glad to see you there.
All my love.
P.S. Both this weekend and next weekend that is until the 9th of March ( and probably the 10th have to celebrate) I'll be in occasional touch with Reba II's address, which is Box 97, West
Memorial Hall, Indiana University, Bloomington, Indiana.
While I'm thinking of it it's a rotten deal that I have to be floating around the country
on my 21st birthday.
Pittsburgh is absolutely filthy. I'd hate to live here.
- Membership Card for the Roster of Ammunition “Know-How” for LP. [Letter from Klanderman to LP March 11, 1946] [Filed under LP Science: Scientific War Work - Materials re: the Pauling Oxygen Meter, 1940-1947: Box #13.001 Folder #1.2]
- Note from AHP to Dr. Thomas Addis RE: Thanks him for the x-ray report and says that everything is going fine. [Filed under LP Correspondence: Box #2.2, file:(Addis, Thomas 1946-1947)]
- Payroll stub from California Institute of Technology (period ending Feb 28 ‘46) and Bank of America deposit slip for $698.06 [LP Biographical: Business and Financial 4.068, folder 68.2]