William T. Astbury George W. Beadle John Desmond Bernal William Lawrence Bragg Herman R. Branson Dan H. Campbell William B. Castle Robert B. Corey Francis H. C. Crick Max Delbrück Emil Fischer Frank Blair Hanson Maurice Huggins Harvey A. Itano John C. Kendrew Karl Landsteiner Alfred E. Mirsky Carl G. Niemann Linus Pauling Max F. Perutz Frederick Sanger S. Jonathan Singer Theodor (The) Svedberg Alexander R. Todd Warren Weaver Dorothy WrinchView all Key Participants
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Robert B. Corey1897-1971
Robert Corey Papers, 1924-1965 Location: Caltech Institute Archives Address: Mail Code 015A-74, Caltech, Pasadena, California 91125 Size: 2 linear feet Finding Aid: http://bit.ly/WRYWgJ Phone: 626-395-2704 Fax: 626-793-8756 Email: archives@caltech.edu Web: http://archives.caltech.edu/
Correspondence
- Letter from Linus Pauling to Warren Weaver. July 29, 1936.
- Letter from Robert Corey to Linus Pauling. April 30, 1937.
- Letter from Linus Pauling to Robert Corey. May 4, 1937.
- Letter from Robert Corey to Linus Pauling. May 8, 1937.
- Letter from Robert Corey to Linus Pauling. July 3, 1937.
- Letter from Linus Pauling to Warren Weaver. February 23, 1938.
- Letter from Warren Weaver to Linus Pauling. March 2, 1938.
- Letter from Linus Pauling to David Harker. October 17, 1938.
- Letter from Robert Corey to Linus Pauling. January 22, 1940.
- Letter from Linus Pauling to Warren Weaver. October 5, 1944.
- Letter from Linus Pauling to Robert Corey. February 3, 1948.
- Letter from Linus Pauling to Carl Niemann. February 18, 1948.
- Letter from Linus Pauling to Robert Corey. March 3, 1948.
- Letter from Linus Pauling to Carl Niemann. April 1, 1948.
- Memorandum from Robert Corey to Linus Pauling. May 25, 1950.
- Letter from Linus Pauling to Herman Branson. October 6, 1950.
- Letter from Linus Pauling to Sidney Weinbaum. November 13, 1950.
- Letter from Linus Pauling to Dennis Flanagan. March 8, 1951.
- Letter from Linus Pauling to E. Bright Wilson, Jr. March 15, 1951.
- Letter from Linus Pauling to N.V. Sidgwick. May 1, 1951.
- Letter from J.D. Bernal to Linus Pauling. June 22, 1951.
- Letter from Linus Pauling to W.L. Bragg. July 16, 1951.
- Memorandum from Linus Pauling to Robert Corey. July 24, 1951.
- Memorandum from Linus Pauling to Robert Corey. July 26, 1951.
- Letter from Max Perutz to Linus Pauling. August 17, 1951.
- Letter from Linus Pauling to Max Perutz. August 29, 1951.
- Memorandum from Walter Schroeder to Linus Pauling. October 30, 1951.
- Memorandum from Walter Schroeder to Robert Corey. December 6, 1951.
- Memorandum from John E. Leonard to Linus Pauling. January 7, 1952.
- Letter from Linus Pauling to W. Lotmar, January 9, 1952.
- Memorandum from Linus Pauling to Leonard Rack. March 3, 1952.
- Memorandum from John E. Leonard and Harry L. Yakel to Linus Pauling. March 29, 1952.
- Letter from Linus Pauling to Maurice Huggins. April 2, 1952.
- Letter from Eddie Hughes to Linus Pauling. May 2, 1952.
- Letter from Linus Pauling to Eddie Hughes. May 2, 1952.
- Letter from Eddie Hughes to Linus Pauling. May 8, 1952.
- Letter from Linus Pauling to Alexander Todd. May 12, 1952.
- Memorandum from Walter Schroeder to Linus Pauling. November 6, 1952.
- Letter from Linus Pauling to Alexander Todd. February 19, 1953.
- Memorandum from Rafael Pasternak to Linus Pauling. February 15, 1954.
- Memorandum from Linus Pauling to Robert Corey. September 8, 1954.
- Letter from Linus Pauling to Alexander Rich. September 7, 1955.
Pictures and Illustrations
Published Papers and Official Documents
Manuscript Notes and Typescripts
- "Report on Research in Chemistry at the California Institute of Technology Done with
the Support of the Rockefeller Foundation, 1939-1940." April 6, 1940.
- "Confidential Monthly Report." January 1, 1949.
- "The Structure of Proteins: Two Hydrogen-Bonded Helical Configurations of the Polypeptide
Chain." February 28, 1951.
- "The Structure of Synthetic Polypeptides." March 1951.
- "The Pleated Sheet, A New Layer Configuration of Polypeptide Chains." March 1951.
- "The Polypeptide-Chain Configuration in Hemoglobin and Other Globular Proteins." March 1951.
- "The Structure of Fibrous Proteins of the Collagen-Gelatin Group." March 1951.
- "The Collagen Structure" March 3 - 24, 1951.
- "The Structure of the Silk Fibroin" July 7, 1951 - April 4, 1952.
- "Polyglycine" July 15, 1951 - November 30, 1952.
- "Rudall's Photograph of Fibrin" July 21, 1951 - January 14, 1952.
- Pauling Diary: "France and England 1952 / Also Toronto." 1952.
- "The 4.5 residue Helix" September 27 - October 3, 1952.
- "The Cis-Trans Pleated Sheets" November 1 - 2, 1952.
- "The Stochastic Method and the Structure of Proteins." July 29, 1953.
- "Third Report on Collagen." January 19, 1954.
- "The Molecular Structure of Hair and Similar Fibrous Proteins." July 1954.
- "Molecular Structure of Proteins." January 18, 1967.
- "Molecular Complementariness and Biological Specificity" and "The Structure of Proteins." February 26 - 28, 1968.
- "Robert Brainard Corey." May 5, 1971.
- "Bernal's Contributions to Structural Chemistry." November 18, 1971.
- "The Molecular Basis of Biological Specificity." March 5, 1974.
- "The Discovery of the Alpha Helix." September 1982.
- "The Discovery of the Pleated-Sheet Structures of Proteins." April 7, 1983.
- "How My Interest in Proteins Developed." January 12, 1993.
Quotes
"I think it has really been very much worthwhile for me to get away for this period
of time, under circumstances favorable to my thinking over questions and trying to
find their solution."
Linus Pauling. Letter to Robert Corey. March 3, 1948.
"He and I together decided that he should work on the determination of the structure
of some crystals of amino acids and simple peptides. When I say that he and I together
made this decision, I may not be quite right. It is not unlikely that he had already
made the decision, and that he arranged to have me agree with him, in such a way that
I would think that we had made the decision together. I learned later that he was
very good at this..."
Linus Pauling. "Robert Brainard Corey." May 3, 1971.
"On my return to Pasadena in the fall of 1948 I talked with Professor Corey about
the alpha helix and the gamma helix, and also with Dr. Herman Branson, who had come
for a year as a visiting professor. I asked Dr. Branson to go over my calculations,
and in particular to see if he could find any third helical structure. He reported
that the calculations were all right, and that he could not find a third structure."
Linus Pauling. "The Discovery of the Alpha Helix." September 1982.
"...[T]hree ways of folding polypeptide chains have turned out to constitute the most
important secondary structures of all proteins. Dr. Corey, to some extent with my
inspiration, designed molecular models of several different kinds that were of much
use in the later effort to study other methods of folding polypeptide chains. I used
these units to make about 100 different possible structures for folding polypeptide
chains."
Linus Pauling. "The Discovery of the Alpha Helix." September 1982.
"[Corey and I] reached the conclusion, as did Crick, that in the alpha-keratin proteins
the alpha helices are twisted together into ropes or cables. This idea essentially
completed our understanding of the alpha-keratin diffraction patterns."
Linus Pauling. "The Discovery of the Alpha Helix." September 1982.
"During a single year, using his own x-ray equipment, Corey made great strides into
the protein puzzle. He showed that in the crystalline dipeptide diketopiperazine
(a simplified analogue of amino acids), the amide bonds were coplaner, strongly suggesting
the presence of a resonance structure - observations that fit precisely with Pauling's
studies of the amide bond in urea during the early 1930s."
Lily E. Kay. The Molecular Vision of Life: Caltech, The Rockefeller Foundation and the Rise of
the New Biology (New York: Oxford University Press). 1993.
"While my own work at Caltech had nothing to do with protein structure, Pauling used
to talk to me occasionally about his models and what one could learn from them. In
his lecture, he had talked about spirals. In conversation a few days later, I told
him that for me the word "spiral" referred to a curve in a plane. As his polypeptide
coils were three-dimensional figures, I suggested they were better described as "helices."
Pauling's erudition did not stop at the natural sciences. He answered, quite correctly,
that the words "spiral" and "helix" are practically synonymous and can be used almost
interchangeably, but he thanked me for my suggestion because he preferred "helix"
and declared that he would always use it henceforth. Perhaps he felt that by calling
his structure a helix there would be less risk of confusion with the various other
models that had been proposed earlier. In their 1950 short preliminary communication,
Pauling and Corey wrote exclusively about spirals, but in the series of papers published
the following year the spiral had already given way to the helix. There was no going
back. A few years later we had the DNA double helix, not the DNA double spiral. The
formulation of the α-helix was the first and is still one of the greatest triumphs
of speculative model building in molecular biology, and I am pleased that I helped
to give it its name."
Jack Dunitz. "La Primavera." (unpublished manuscript) 2011. Audio Clips
Video Clips
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