Linus Pauling and the Structure of Proteins: A Documentary History All Documents and Media  
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104 documents

Notes re: "On Cross Reactions of Immune Sera to Azoproteins." 1930s.
Notes by Linus Pauling on a publication by Karl Landsteiner and J. van der Scheer, which originally appeared in The...  View all information. 

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Notes re: "Immunochemistry." 1930s.
Notes by Linus Pauling on a publication by M. W. Chase and Karl Landsteiner, which originally appeared in Annual Review...  View all information. 

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Notes re: the structures of insulin, gelatin, zeni and lysine, 1930s.
View all information. 10 pages total.

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Notes re: protein structure research conducted by William T. Astbury, 1930s.
View all information. 

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"Rockefeller Fund." October 24, 1933.
Notes re: the need to take quick action in applying to the Rockefeller Foundation for funds to support "qualitative work...  View all information. 

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"Brief Account of Research in Chemistry Supported by Grant from the Rockefeller Foundation." October 24, 1933.
View all information. 

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"Vanadium in Ascidia" 1935.
View all information. 

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Pauling Diary: "Addresses." 1935.
This diary is devoted to issues surrounding the California Institute of Technology. Many of Pauling’s entries focus on the...  View all information. 55 pages total.

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"Flavine" December 24, 1935.
View all information. 

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"The Structure of Proteins." 1936.
Published as "On the Structure of Native, Denatured, and Coagulated Proteins."  View all information. 13 pages total.

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Notes re: projects likely to be funded by the Rockefeller Foundation. March 6, 1936.
View all information. 

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"On the Structure of Antibodies and Other Proteins." 1937.
View all information. 16 pages total.

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"A Program for the Development of Organic Chemistry at the California Institute of Technology and for an Attack on Biological Problems by the Methods of Organic Chemistry and Structural Chemistry." 1937.
A proposal developed for submission to the Rockefeller Foundation.  View all information. 9 pages total.

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Pauling Diary: "1937. Also 1938-9." 1937 - 1939.
Much of Linus Pauling’s diary contains information on his colleagues including their work, salaries, and future positions. The diary...  View all information. 56 pages total.

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"A Program for the Development of Organic Chemistry at the California Institute of Technology and for an Attack on Biological Problems by the Methods of Organic Chemistry and Structural Chemistry." August 7, 1937.
Grant proposal submitted to the Rockefeller Foundation.  View all information. 9 pages total.

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"Notes on talks between Dr DM Wrinch and Linus Pauling." January 26, 1938.
Notes by Pauling and Wrinch resulting from their discussions on their differing opinions concerning protein structures.  View all information. 6 pages total.

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"Report on the work of Dr. Dorothy Wrinch." March 31, 1938.
Pauling's summary of his discussions on proteins structures with Dorothy Wrinch as compiled for Warren Weaver of the Rockefeller Foundation.  View all information. 

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"Proteins." April 22 - May 17, 1938.
Research notebook containing early notes by Pauling on antibodies and antigens.  View all information. 5 pages total.

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"The Geometrical Attack on Protein Structures." approx. 1939.
A discussion by Dorothy Wrinch of the cyclol theory of protein structures, including an examination of Pauling and Niemann's arguments...  View all information. 21 pages total.

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Notes re: oxidation of muscle cells during contracation, June 1939.
View all information. 12 pages total.

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"The Nature of the Intermolecular Forces Operative in Biological Processes." 1940.
View all information. 5 pages total.

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"Question: Are two or more antigen molecules needed to make an antibody?" March 3, 1940.
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"Report on Research in Chemistry at the California Institute of Technology Done with the Support of the Rockefeller Foundation, 1939-1940." April 6, 1940.
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"The Polypeptide Chain." June 1940.
View all information. 8 pages total.

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"A Proposed Project of Experimental Investigation of the Structure of Antibodies and the Nature of Immunological Reactions." March 18, 1941.
Proposal issued to the Rockefeller Foundation.  View all information. 

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"Theory of Precipitation Reaction." September 21, 1941.
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"Antigen-Antibody Interactions" and "Antigen-Antibody-Haptene Interaction." December 24, 1941 - January 20, 1942.
View all information. 36 pages total.

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"Hapten Inhibition for Heterogeneous Antiserum." August 5, 1943.
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"A Note on the Serological Activity of Denatured Antibodies." 1944.
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"Work in Immunochemistry at the California Institute of Technology." 1944 - 1945.
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"Molecular Structure and Biological Specificity." July 17, 1947.
View all information. 12 pages total.

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No Title ["derivation of Clausius-Mosotti equation"]. May 11, 1948.
Oxford Lectures, Lecture 4, England  View all information. 

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"Confidential Monthly Report." January 1, 1949.
Delivered to the Rockefeller Foundation. [LP Annotation: "Biog. File, LP p. 3 on"]  View all information. 20 pages total.

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"Difference in Electrophoretic Behavior of Sickle Cell Hemoglobin and Normal Human Hemoglobin." April 27, 1949.
Used in a talk advertised as "Sickle Cell Anemia, a Molecular Disease." National Academy of Sciences, Annual Meeting, Washington, D.C. [LP did not attend]  View all information. 

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"Sickle Cell Anemia, A Molecular Disease." 1950.
Letter to the Editor of Nature.  View all information. 8 pages total.

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Notes re: the structure of Poly Methyl L Glutamate, 1950s.
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Notes re: values for interatomic distances in collagen molecules, 1950s.
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"The Gerontology of Viruses." 1950s.
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Notes re: bond distances for the α-helix and the γ-helix, March 26, 1950.
View all information. 6 pages total.

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Linus Pauling note to self concerning research on succinic dehydrogenase. April 12, 1950.
Pauling writes to himself about research by Quastel and Kun on succinic dehydorgenase, its proteins, and the effects of certain...  View all information. 

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Linus Pauling note to self concerning the configurations of stable states of proteins. October 10, 1950.
Pauling documents published research by himself and by others concerning the "configuration of the extent of the polypeptide chain." ...  View all information. 

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Pauling Diary: "Westinghouse 1951 Diary." 1951.
This diary contains notes on Linus Pauling’s meetings, public appearances, and travels. Likewise, Pauling made entries regarding research work...  View all information. 42 pages total.

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"The Structure of Proteins: Two Hydrogen-Bonded Helical Configurations of the Polypeptide Chain." February 28, 1951.
View all information. 12 pages total.

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"The Structure of Synthetic Polypeptides." March 1951.
View all information. 11 pages total.

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"The Structure of Hair, Muscle, and Related Proteins." March 1951.
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"The Structure of Feather Rachis Keratin." March 1951.
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"The Pleated Sheet, A New Layer Configuration of Polypeptide Chains." March 1951.
View all information. 20 pages total.

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"The Polypeptide-Chain Configuration in Hemoglobin and Other Globular Proteins." March 1951.
View all information. 8 pages total.

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"The Structure of Fibrous Proteins of the Collagen-Gelatin Group." March 1951.
View all information. 5 pages total.

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"The Collagen Structure" March 3 - 24, 1951.
View all information. 40 pages total.

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Linus Pauling note to self regarding the structure of proteins. March 5, 1951.
A Pauling note to self defining the ways in which the helical structures for the polypeptide chain that he and...  View all information. 

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Notes re: the γ-Helix, March 10, 1951.
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Notes re: Crystalline Muscle, March 10, 1951.
View all information. 16 pages total.

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Notes re: the α-Helix, March 11, 1951.
View all information. 8 pages total.

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Notes re: Myosin Muscle, March 29, 1951.
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"The Structure of the Silk Fibroin" July 7, 1951 - April 4, 1952.
View all information. 56 pages total.

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Linus Pauling note to self concerning taste and molecular shape. July 9, 1951.
Pauling writes a note to himself quoting the July 1951 Scientific American. The quote is from a 1846 study...  View all information. 

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"Polyglycine" July 15, 1951 - November 30, 1952.
View all information. 22 pages total.

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"Rudall's Photograph of Fibrin" July 21, 1951 - January 14, 1952.
View all information. 22 pages total.

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Notes re: the structure of the satonia silk fibroin, August 2, 1951 - January 20, 1952.
View all information. 6 pages total.

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Notes re: Lotmar & Picken's Muscle, October 20, 1951.
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Notes re: Crystallized Muscle, December 14, 1951.
View all information. 15 pages total.

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Pauling Diary: "France and England 1952 / Also Toronto." 1952.
Pauling's diary includes a series of entries regarding scientific research while in Europe and Canada. Among these entries are...  View all information. 75 pages total.

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Notes: "Reconsideration of crystallized muscle" January 9, 1952.
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Notes: "Remeasurement of Lotmar-Picken" January 20, 1952.
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Notes re: the collagen helix, March 25 - April 23, 1952.
View all information. 18 pages total.

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"A Report on Collagen" April 12, 1952.
View all information. 6 pages total.

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"Collagen" May 11, 1952.
Notes re: bond lengths in meridional reflections in collagen.  View all information. 

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Notes re: the lattice structure of silk, May 14, 1952.
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"Collagen" May 18, 1952.
Notes re: the calculation of interstities from collagen residues.  View all information. 

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"The Department of State and the Structure of Proteins." June 1952.
Unpublished manuscript by Linus Pauling concerning the impact made upon his research by the denial of his passport.  View all information. 17 pages total.

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"The Antiparallel cis-trans-chain Sheet" June 2, 1952.
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"The Forces Operating between Polypeptide Chains." August 6 - 8, 1952.
Discussion of the Faraday Society on the Physical Chemistry of the Proteins, Cambridge University, England.  View all information. 

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Notes re: collagen research conducted by Hofmann, Nemetschek and Grassmann. September 1952.
View all information. 

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"Compound Helixes" September 19 - October 15, 1952.
A series of notes regarding alpha-Keratin, Interstitial Matter, Feather Keratin, and the alpha-helix  View all information. 41 pages total.

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"The 4.5 residue Helix" September 27 - October 3, 1952.
View all information. 9 pages total.

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"Collagen" October 4 - 7, 1952.
Notes re: problems with the old collagen structural model.  View all information. 

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"Effect of Proline or Hydroxyproline on α Helix" October 15, 1952.
View all information. 5 pages total.

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Notes re: amino acid research conducted by Walter Schroeder and colleagues, October 28, 1952.
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"The Cis-Trans Pleated Sheets" November 1 - 2, 1952.
View all information. 13 pages total.

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"The Antiparallel Chart Rippled Sheet" November 12 - 24, 1952.
View all information. 6 pages total.

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"Silk Fibroin - Reconsideration" November 14, 1952.
View all information. 10 pages total.

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"Collagen" January 1 - 3, 1953.
Notes re: the compound helical structure of collagen.  View all information. 5 pages total.

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"The 94.6-Å Unit of Feather Rachis" approx. February 1953.
View all information. 

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"Linus Pauling Notebook. Solvay Congress 1953" April 1953.
.  View all information. 57 pages total.

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"Compound helixes with 1/3 of H. bonds missing" May 17 - 24, 1953.
View all information. 8 pages total.

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Pauling Diary: "Trips to Germany, Sweden, and Denmark, July and August 1953" July - November 1953.
.  View all information. 155 pages total.

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"The Stochastic Method and the Structure of Proteins." July 29, 1953.
Speech delivered at the opening session of the Thirteenth International Congress of Pure and Applied Chemistry, Stockholm, Sweden.  View all information. 19 pages total.

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"Third Report on Collagen." January 19, 1954.
Note to Self by Linus Pauling.  View all information. 

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"The Molecular Structure of Hair and Similar Fibrous Proteins." July 1954.
View all information. 27 pages total.

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"Biographical Notes Re: Thomas Addis." February 1, 1955.
View all information. 6 pages total.

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"The Future of Enzyme Research." November 1, 1955.
Fourth Edsel B. Ford Lecture, Henry Ford Hospital, Detroit, Michigan.  View all information. 9 pages total.

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"Astbury - Tropomyosin Actin" August 12, 1956.
Pauling Notes re: "X-Ray and Electron Microscope Studies, and their Cytological Significance, of the Recently-Discovered Muscle Proteins, Tropomyosin and Actin," by W. T. Astbury.  View all information. 14 pages total.

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"Factors Affecting the Structure of Hemoglobins and Other Proteins." June 20, 1957.
View all information. 10 pages total.

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"A Proposal for an International Institute for the Determination of the Structure of Globular Proteins, Nucleic Acids, and Other Macromolecules Important to Life." September 5 - 9, 1961.
Prepared for the Seventh Conference on Science and World Affairs, Stowe, Vermont.  View all information. 

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"Molecular Structure of Proteins." January 18, 1967.
Presidential Address delivered at the International Symposium on Conformation of Biopolymers, University of Madras, India.  View all information. 9 pages total.

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"Molecular Complementariness and Biological Specificity" and "The Structure of Proteins." February 26 - 28, 1968.
Lectures in Molecular Biology, University of California, Los Angeles.  View all information. 9 pages total.

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"Robert Brainard Corey." May 5, 1971.
Delivered at Corey's memorial meeting, California Institute of Technology, Pasadena.  View all information. 6 pages total.

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"Bernal's Contributions to Structural Chemistry." November 18, 1971.
View all information. 7 pages total.

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"The Molecular Basis of Biological Specificity." March 5, 1974.
View all information. 19 pages total.

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"Molecular Complementariness and Serological Specificity." October 31, 1974.
View all information. 8 pages total.

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"The Discovery of the Alpha Helix." September 1982.
View all information. 16 pages total.

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"The Discovery of the Pleated-Sheet Structures of Proteins." April 7, 1983.
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"How My Interest in Proteins Developed." January 12, 1993.
View all information. 9 pages total.

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