Linus Pauling and the Structure of Proteins: A Documentary History All Documents and Media  
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Key Participants

William T. Astbury
George W. Beadle
John Desmond Bernal
William Lawrence Bragg
Herman R. Branson
Dan H. Campbell
William B. Castle
Robert B. Corey
Francis H. C. Crick
Max Delbrück
Emil Fischer
Frank Blair Hanson
Maurice Huggins
Harvey A. Itano
John C. Kendrew
Karl Landsteiner
Alfred E. Mirsky
Carl G. Niemann
Linus Pauling
Max F. Perutz
Frederick Sanger
S. Jonathan Singer
Theodor (The) Svedberg
Alexander R. Todd
Warren Weaver
Dorothy Wrinch

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Portrait of Alfred E. Mirsky
Portrait of Alfred E. Mirsky, 1960s.
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Alfred E. Mirsky


Alfred E. Mirsky Papers, 1915-1986 (1936-1975, bulk)
Location: The Rockefeller Archive Center
Address: 15 Dayton Avenue, Sleepy Hollow, New York 10591
Size: 36 cubic feet
Finding Aid:
Phone: 914-631-4505  Fax: 914-631-6017
Email:  Web:



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"In suggesting that hydrogen bonds determined the three-dimensional configuration of proteins - and thus their biological specificity - Pauling and Mirsky enunciated a fundamental relation between molecular structure and biological function. It was also one of the cornerstones of Pauling's conception of molecular architecture, a metaphor and method for explaining life in health and disease, which would lend legitimacy to the molecular biology enterprise."

Lily E. Kay. The Molecular Vision of Life: Caltech, The Rockefeller Foundation and the Rise of the New Biology (New York: Oxford University Press). 1993.

"This was a fortunate arrangement. Not only did Mirsky teach me how to handle proteins in the laboratory - they are far more delicate than inorganic substances - but he also gave me a great amount of information about the properties of proteins and especially about denaturation of proteins."

Linus Pauling. "How My Interest in Proteins Developed." January 12, 1993.

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