Letter from Linus Pauling to Richard O. Boyer. February 24, 1959. Page 1  Larger Images / More Information. 1 p.  View Transcript

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Activity Listings

• Check from AHP to Allen Cleaners and Dryers for $4.75. [Filed under LP Biographical: (Business and Financial: Bank Statements and Canceled Checks, December 1957-December 1959), Box #4.025, Folder #25.2] [Also filed under LP Biographical: (Business and Financial: Check Registers, 1951-1960), Box #4.075, Folder #75.6]
• Check from AHP to Bullock's for $1.72. [Filed under LP Biographical: (Business and Financial: Bank Statements and Canceled Checks, December 1957-December 1959), Box #4.025, Folder #25.2] [Also filed under LP Biographical: (Business and Financial: Check Registers, 1951-1960), Box #4.075, Folder #75.6]
• Check from AHP to Friends Committee on Legislation for $10.00. [Filed under LP Biographical: (Business and Financial: Bank Statements and Canceled Checks, December 1957-December 1959), Box #4.025, Folder #25.2] [Also filed under LP Biographical: (Business and Financial: Check Registers, 1951-1960), Box #4.075, Folder #75.6]
• Check from AHP to Herman Koller for $7.60. [Filed under LP Biographical: (Business and Financial: Bank Statements and Canceled Checks, December 1957-December 1959), Box #4.025, Folder #25.2]
• Check from AHP to Mira Loma Mutual Water Company for $16.12. [Filed under LP Biographical: (Business and Financial: Bank Statements and Canceled Checks, December 1957-December 1959), Box #4.025, Folder #25.2] [Also filed under LP Biographical: (Business and Financial: Check Registers, 1951-1960), Box #4.075, Folder #75.6]
• Check from AHP to Vroman's for $48.58. [Filed under LP Biographical: (Business and Financial: Bank Statements and Canceled Checks, December 1957-December 1959), Box #4.025, Folder #25.2] [Also filed under LP Biographical: (Business and Financial: Check Registers, 1951-1960), Box #4.075, Folder #75.6]
• Check from LP to A and E Auto Repair for $68.85. [Filed under LP Biographical: (Business and Financial: Bank Statements and Canceled Checks, December 1957-December 1959), Box #4.025, Folder #25.2]
• Check from LP to California Institute of Technology Bookstore for $47.87. [Filed under LP Biographical: (Business and Financial: Bank Statements and Canceled Checks, December 1957-December 1959), Box #4.025, Folder #25.2] [Also filed under LP Biographical: (Business and Financial: Check Registers, 1957-1962), Box #4.076, Folder #76.1]
• Check from LP to California Institute of Technology for $19.38. [Filed under LP Biographical: (Business and Financial: Bank Statements and Canceled Checks, December 1957-December 1959), Box #4.025, Folder #25.2] [Also filed under LP Biographical: (Business and Financial: Check Registers, 1957-1962), Box #4.076, Folder #76.1]
• Check from LP to G.F. Sprague for $6.00. [Filed under LP Biographical: (Business and Financial: Bank Statements and Canceled Checks, December 1957-December 1959), Box #4.025, Folder #25.2]
• Check from LP to Gray Line Company for $125.60. [Filed under LP Biographical: (Business and Financial: Bank Statements and Canceled Checks, December 1957-December 1959), Box #4.025, Folder #25.2] [Also filed under LP Biographical: (Business and Financial: Check Registers, 1957-1962), Box #4.076, Folder #76.1]
• Check from LP to Inghan, Coates, and Payne for $26.00. [Filed under LP Biographical: (Business and Financial: Bank Statements and Canceled Checks, December 1957-December 1959), Box #4.025, Folder #25.2] [Also filed under LP Biographical: (Business and Financial: Check Registers, 1957-1962), Box #4.076, Folder #76.1]
• Check from LP to Kloke's for $189.69. [Filed under LP Biographical: (Business and Financial: Bank Statements and Canceled Checks, December 1957-December 1959), Box #4.025, Folder #25.2] [Also filed under LP Biographical: (Business and Financial: Check Registers, 1957-1962), Box #4.076, Folder #76.1]
• Check from LP to Mineralogical Society of America for $4.00. [Filed under LP Biographical: (Business and Financial: Bank Statements and Canceled Checks, December 1957-December 1959), Box #4.025, Folder #25.2] [Also filed under LP Biographical: (Business and Financial: Check Registers, 1957-1962), Box #4.076, Folder #76.1]
• Check from LP& AHP to California Institute of Technology for $6.00. [Filed under LP Biographical: (Business and Financial: Check Registers, 1957-1962), Box #4.076, Folder #76.1]
• Invoice from A&E Auto Repair to LP for $68.85. [Filed under LP Biographical: (Business and Financial: Assorted Bills, Receipts, and Invoices, 1951-1962), Box #4.060, Folder #60.4]
• Letter from Dr. David Pressman, Roswell Park Memorial Institute, State of New York Department of Health, to LP RE: Reminds him that he recommended Dr. Murray V. King to them to head their Biophysics Department, thanks him, tells him about the process of the interview and the seminar, says their Director was concerned that he hadn't published much and only offered him the position as Principal Cancer Research Scientist, says King wasn't interested and seems settled where he is, and asks if LP has any other suggestions. [Letter from LP to Pressman December 2, 1958] [Filed under LP Correspondence: (K: Correspondence, 1959), #201.3]
• Letter from Dr. Walter Bauer, The Helen Hay Whitney Foundation to LP RE: Regrets to accept LP's resignation from the Scientific Advisory Committee of the Helen Hay Whitney Foundation. On behalf of the Board of Trustees and the Scientific Advisory Committee, Bauer thanks LP for his time and effort. [Letters from LP to Bauer January 30, 1959, March 11, 1959] [Filed under LP Science: Helen Hay Whitney Foundation—Scientific Advisory Committee: Correspondence 1954-1959: Box #15.002, Folder #2.5]
• Letter from Frank L. Lambert, Occidental College, to LP RE: Invites LP to come to Occidental to speak and show a preview of the forthcoming film on molecular vibrations in August. [Letter from LP to Lambert February 27, 1959] [Filed under LP Correspondence: (P: Correspondence) #313.7]
• Letter from Jaques Cattell, Editor, American Men of Science, to LP RE: Encloses his biography to be corrected for inclusion in the Tenth Edition of American Men of Science, asks him to nominate colleagues he considers eligible and indicate if he wants to take advantage of his discount for the Tenth Edition, tells about the change in the arrangement of the book, and says the Tenth Edition will be issued in four parts to be shipped nine months apart and billed at the same intervals. [Subscription order form attached (Note at top in pencil: "returned and set ordered (42._) on February 24, 1959")] [Filed under LP Correspondence: (A: Correspondence, 1959), #13.2]
• Letter from Joan Harris, Secretary to LP, to H. B. Bennett, Bennett Travel Agency, RE: Encloses tickets which were not used between Eugene and Portland. Inquires about obtaining a refund for the tickets. [Filed under LP Correspondence: (T: Correspondence, 1959), #411.4]
• Letter from Joan Harris, Secretary to LP, to J. J. Fritz, Pennsylvania State University, RE: Provides information about LP's current travel plans from East Lansing to University Park in April. Discusses tentative itinerary options. [Letter from Fritz to LP February 3, 1959, Letter from Fritz to Harris March 3, 1959] [Filed under LP Speeches: 1959s.17]
• Letter from Joan Harris, Secretary to LP, to Robert H. Sollen, The Press-Courier, RE: Says LP would be pleased to take part in an interview with Sollen. [Letter from Sollen to LP February 21, 1959, Letter from Robert Sollen to LP March 4, 1959] [Filed under LP Correspondence: (S:Correspondence, 1959), #380.3]
• Letter from LP to Ann Crawford RE: Says he and Professor Barclay Kamb thank her for her letter and the clippings she enclosed, feels their exchange of letters with the editor of the New York Times has succeeded in educating the readers of that newspaper, and encloses a reprint of their paper on the subject and a transcript of the debate he had with Dr. Teller last year. [Letter from Crawford to LP May 8, 1959] [Filed under LP Correspondence: (C: Correspondence, 1959), #75.2]
• Letter from LP to David Whitney, World Book Encyclopedia, RE: Declines the invitation to rewrite an article on Matter for the World Book Encyclopedia. [Letter from Whitney to LP February 18, 1959] [Filed under LP Correspondence: (W: Correspondence, 1959), #444.7]
• Letter from LP to Dolores Ziff, Publicity Manager, Philadelphia Office, J. B. Lippincott Company RE: Says he has read Pat Frank's new book Alas, Babylon with great interest and pleasure, believes it gives a realistic account of life in the U. S. if there were to be a small nuclear war, says his only criticism is that the author underestimated the possible nuclear attack and effect of fallout, and believes it will give the reader cause to contemplate the menacing nuclear future. [Ziff to LP February 13, 1959] [Filed under LP Correspondence: (L: Correspondence, 1959), #231.5]
• Letter from LP to Dr. J. J. Antel, Department of Public Health and Welfare, County of San Mateo RE: Says he was pleased to receive his invitation to visit the Adult and Child Psychiatric Clinic of San Mateo when he is in San Francisco for the meeting of the American Ortho Psychiatric Association, and says he is sorry he can't accept because his visit in San Francisco will be very short. [Letter from Antel to LP January 19, 1959] [Filed under LP Correspondence: (A: Correspondence, 1959), #13.2]
• Letter from LP to Dr. Lewis R. Lancaster, First Methodist Church, Burbank, California RE: Wishes he could come to speak in April, and explains that he is making a trip to the eastern U. S. in April so he can't accept their invitation. [Letter from Lancaster to LP February 19, 1959] [Filed under LP Correspondence: (L: Correspondence, 1959), #231.5]
• Letter from LP to Dr. Rodolfo Busch, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires RE: Remembers their talk about PtO, says he does not have any more information about this question, judges that it is highly probable that the compound synthesized under LP's direction is not PtO but another oxide of platinum, says as he is now working in chemistry related to medicine he has no opportunity to carry on further work on PtO, and says he would be grateful if Busch would state in his publication that LP agrees it is unlikely they had a sample of PtO. [Letter from LP to Busch February 5, 1959] [Filed under LP Correspondence: (B: Correspondence, 1959), #39.2]
• Letter from LP to Gabriel Chuchani, Instituto Venezolano de Investigaciones Cientificas, RE: Declines the invitation to attend the opening conference of the IX Annual Convention of the Venezuelan Association for the Advancement of Science. [Letter from Chuchani to LP February 20, 1959] [Filed under LP Correspondence: (V: Correspondence, 1959), #427.19]
• Letter from LP to Gunnar Jahn, Director, Valutaavdelingen Norges Bank, RE: Tells Jahn of his plan to set up a World Academy of Sciences, but is that he is still trying to reach a decision about the legal basis of this organization. Believes that Norway would be a suitable nation to grant a charter to the World Academy of Sciences, because Norway is associated in the minds of people all over the world with the idea of world peace. [Letter from Jahn to LP March 2, 1959] [Filed under LP Science: (Wold Academy of Sciences, 1958-1963), Box #14.043, Folder #43.1]
• Letter from LP to Gunnar Jahn, Valutaavdelingen Norges Bank, RE: Has been working with Professor Barclay Kamb in carrying out a thorough statistical analysis of Dr. Miriam P. Finkel's data the decrease in life expectancy and the occurrence of tumors in mice injected with strontium-90. Discovered that the conclusion she reached was completely unjustified by her data. Has been trying to prevent the second Geneva Conference on Bomb Tests from coming to an end without an agreement having been made. [Filed under LP Science: (World Academy of Sciences, 1958-1963), Box #14.043, Folder #43.1]
• Letter from LP to John Bollens, American Friends Service Committee, RE: LP's schedule will not permit him to come to Chicago on March 28, as he is tied up with a speech to the psychiatrists. LP wishes the committee a successful Week for World Peace. [Letter from Bollens February 16, 1959] [Filed under LP Peace: (Assorted Peace Groups, Am), Box #4.009, Folder #9.4]
• Letter from LP to Maurice B. Visscher, University of Minnesota, RE: Sends Visscher reprints of his paper on carbon-14 and the paper by Professor Kamb and him on strontium-90. [Letter from Visscher to LP February 10, 1959] [Filed under LP Correspondence: (V: Correspondence, 1959), #427.19]
• Letter from LP to Merril Eisenbud, United States Atomic Energy Commission, RE: Says he believes Eisenbud's letter, regarding a statement made by Eisenbud about fallout, to Dennis Flanagan is misleading. [Letter from Eisenbud to Flanagan February 16, 1959, Letter from Eisenbud to LP June 12, 1959] [Filed under LP Manuscripts of Articles: 1959a.5]
• Letter from LP to Morris Goodman, Oakland Co. Comm. for a Sane Nuclear Policy, RE: Declines the invitation to attend a reception in his honor. Outlines details of his upcoming trip and lectures in Detroit. Suggests that he may be available for a luncheon during the visit. [Letter from Goodman to LP February 19, 1959, Letter from Goodman to LP March 7, 1959] [Filed under LP Speeches: 1959s.15]
• Letter from LP to Mr. Richard Boyer, Editorial Department, Physicians News Service. [Letter from Mr. Boyer to LP February 20, 1959] [Filed under LP Science: Box #11.088, Folder #88.14]

  25 February 1959

  Mr. Richard O. Boyer

  Editorial Department

  Physicians News Service, Inc.

  130 East 59th Street

  New York 22, New York

  Dear Mr. Boyer

  In answer to your letter of 20 February, I am glad to comment on the questions that you asked.

  1. I think that chemical intervention to correct enzyme abnormalities or deficiencies will become a practical clinical procedure in the not very distant future. For example, in the case of a hereditary enzyme abnormality or deficiency that causes trouble because of the piling up of the substrate that ordinarily is converted into other substances by the enzyme, the treatment might involve simply the decrease in amount of the substrate ingested by the patient. This treatment is already in use: for example, milk is removed from the diet for galactosemics, and phenylalanine is removed from the diet for phenylketonurics.

  I enclose a reprint of a paper in which I have suggested that within fifty years it will be possible to make synthetic substances with enzyme activity, and to use these artificial enzymes in the control of diseases resulting from abnormal or deficient enzymes.

  Another possibility is that an abnormal enzyme manufactured by a patient because of a genetic abnormality may be made effective through the combination with a simple chemical substance.

  2. I do not have any special knowledge about clinical work on chemical intervention to rectify metabolic abnormalities due to enzyme change from genic mutation.

  3. I think that it may well be possible in some cases to make clinical use of transduction. I think that the probability of successful use of transduction is especially high in the case of diseases in which, because of genic abnormality, the patient fails to manufacture an enzyme, or manufactures an abnormal enzyme that will not work. It might be that in some cases modification of cells by transduction, with use of deoxyribonucleic acid, or implantation of cells, may be done in such a way that a satisfactory amount of the enzyme is manufactured by the patient.

  Sincerely yours,

  Linus Pauling:LL

  Enclosure

• Letter from LP to Neal Cornell, Student Affiliates of Southern California. RE: Informs him that his schedule is too heavy for him to come in early May. [Filed under LP Correspondence: (C: Correspondence, 1958) #75.1]
• Letter from LP to Philip H. Spearman, Vancouver Junior Chamber of Commerce, RE: Declines the invitation to take part in a panel discussion of a nuclear test ban. [Letter from Spearman to LP February 18, 1959] [Filed under LP Correspondence: (S:Correspondence, 1959), #380.3]
• Letter from LP to Richard C. La Force, University of California, Berkeley RE: Says he has received a letter from President Richard H. Sullivan of Reed College saying they haven't heard from La Force, and suggests that he get his application in without delay. [Letter from Sullivan to LP February 19, 1959, letter from Wild to LP March 9, 1959] [Filed under LP Correspondence: (La Force, Richard C.), #212.2]
• Letter from LP to Robert Kunin, Rohm and Hass Company, RE: Acknowledges the fact that the Women's International League for Peace and Freedom will be taking over sponsorship of his lecture in Trenton. [Letter from Kunin to LP February 17, 1959] [Filed under LP Speeches: 1959s.18]
• Letter from LP to Sherman Books RE: Says that the book Books is looking for is probably LP's The Nature of the Chemical Bond. [Filed under LP Correspondence: (S: Correspondence, 1959), #380.3]
• Letter from LP to Simon Schachter, National Lawyers Guild, RE: Congratulates Schachter on his 65th birthday and his for his contributions to the betterment of humanity. [Letter from Schachter to LP January 30, 1959] [Filed under LP Correspondence: (S:Correspondence, 1959), #380.3]
• Letter from LP to William Esslinger, RE: Thanks Mr. Esslinger for his book Politics and Science. It impressed him greatly. He also likes the suggestion for printing his book in a cheap paperback, and has discussed it with his publishers. [Letter from LP to Mr. Esslinger, March 18, 1959] [Filed under LP Correspondence: (E: Correspondence, 1960-1969), #113.2]
• Letter from LP to William Esslinger. RE: Thanks him for sending his book. Thanks him for his suggestion for his book. [Filed under LP Correspondence: (E: Correspondence) #112.24]
• Letter from R. A. Javitch, President, Math.-Physics Society, Sir George Williams College, to LP RE: Says he would like to undertake the study of the hemoglobin structure from the NMR viewpoint as a research project next summer, asks for any of LP's reprints on the subject, and says he hopes to find a mathematical relation between structure and pH. [Letter from LP to Javitch March 16, 1959] [Filed under LP Correspondence: (J: Correspondence, 1959), #192.25]
• Letter from Victor Reynolds, Cornell University Press, to LP RE: Says the stock of the last printing of The Nature of the Chemical Bond has been exhausted. Requests that LP reply in order to discuss details of the publication of his book's third edition. [Letter from LP to Reynolds March 27, 1959] [Filed under LP Books: 1960b5.3]
• Letter from W. R. Pritchard, University of Florida, to LP RE: Requests reprints of LP's articles on sickle cell anemia, sickle cell trait and hemoglobins in heath and disease. [Letter from LP to Prichard March 19, 1959] [Filed under LP Correspondence: (P: Correspondence) #313.7]
• Letter from William Freeman, W. H. Freeman and Co., to LP RE: Sends LP a portion of the first draft for general chemistry book by Andrews and Kokes. Says he has low expectations for the book but would like LP's opinion of the draft. [Letter from LP to Freeman February 27, 1959] [Filed under LP Correspondence: (W. H. Freeman and Company, 1959), #439.17]
• Memo from LP to Dr. E. W. Hughes RE: Says he has been interested to read the ms on Nb2Be17, says he is surprised there is no discussion of the interatomic distances, says it may be there is no discussion needed, says the average distance is about the same as in beryllium metal in a technical discussion, and suggests he accept the paper and not ask them to discuss their values of the interatomic distances. [Filed under LP Correspondence: (Hoard, J. Lynn), #159.10]
• Memo from LP to Professor Swift RE: Recommends that Walter M. Meier be reappointed Research Fellow in Chemistry. Describes Meier's credentials and recommends a $5400 salary for him. Memo takes place of LP's February 2 recommendation. [Memo from LP to Kamb February 23, 1959, Memo from Kamb to LP No Date] [Filed under LP Correspondence: (M: Correspondence, 1959), #258.1]
• Note from Mr. and Mrs. Joseph Ryback and sons to LP RE: Wish LP good health and a happy birthday. [Letter from LP to Ryback family March 21, 1959] [Filed under LP Correspondence: (R: Correspondence, 1959), #341.5]