"The Hemoglobin Molecule in Health and Disease." April 19, 1951

Pauling writes on recent discoveries about hemoglobin. He speaks of its possible structure and its relationship with sickle cell anemia, which is the result of an abnormality in a person's hemoglobin molecule. He believs that symptoms came from the formation of nematic type liquid crystals by sickle-cell hemoglobin, which twist the red cells and causes them to become sticky and unable to flow through capillaries. Tissues and organs are then damaged by anoxia. He writes that hemoglobin C and hemoglobin D were recently discovered leading to the recognition of three new diseases: sickle-cell disease C, sickle-cell disease D, and hereditary hemolytic anemia C. He also briefly discusses the presence of fetal hemoglobin in some anemic adults.

"The Hemoglobin Molecule in Health and Disease." Page 1. April 19, 1951
Page 1

"The Hemoglobin Molecule in Health and Disease." Page 2. April 19, 1951
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ID: 1951s.9

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