13 September 1957
Dr. F. H. C. Crick
I had intended to have a chat with you, when I saw you in Cambridge this summer, about
the three hydrogen bonds between guanine and cytosine, but I forgot to do so. Now
I have been jogged into thinking about the matter again by reading your article in
The Scientific American.
I suppose that you saw the paper that Professor Corey and I published in Archives
of Biochemistry and Biophysics last year, in which the matter is discussed. I enclose
It seems to me that there is no justification whatever for continuing to show guanine
and cytosine with only two hydrogen bonds, as you do in The Scientific American article,
both in the text and in the figure. What do you have to say?
With best regards, I am
cc: J. D. Watson