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Memorandum from Linus Pauling to Robert Corey. June 12, 1944.
Pauling discusses a potential post-war program of research on hemoglobin and porphyrins and requests information on the purchasing of a new spectrophotometer.


June 12, 1944

Dr. R. B. Corey

Linus Pauling

I think that a part of our post-war program of intensive research might deal with hemoglobin, including the study of the oxygen-equilibrium curve, the dissociation of hemoglobin by urea, the properties of hemoglobin re-synthesized by adding heme to globin, and so on; and that a part might also deal with porphyrins, which are important both for hemoglobin and for chlorophyll.

What is the progress of our effort to get a new spectrophotometer for Chemistry-13?

Linus Pauling

P.S. I think that we could do a good job on elucidating the nature of the isomerization of porphyrins. Chromatographic methods have been successfully applied by S. Aranoff and M. Calvin, Journal of Organic Chemistry, 8, 205, (1943). They have found six isomers, and I think that they should have isolated seven.

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