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Page 2 Letter from Linus Pauling to William G. Esmond. October 23, 1972.(Large Version) Pauling writes to discuss his recollection of the history of his and Harvey Itano's research on the sickling of erythrocytes containing ferrohemoglobin. Citing from numerous publications that he co-authored, Pauling concludes that he had begun investigations into the inhibition of sickling through the partial transformation of ferrous sickle hemoglobin to ferric methemoglobin well before having received a letter from Esmond in 1954, indicating Esmond's inclinations toward research of a similar nature. Date: October 23, 1972
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