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Letter from Linus Pauling to W. Lotmar, January 9, 1952.
Pauling writes to provide an update on the progress that his laboratory has been making in interpreting the molecular structure of muscle, based on x-ray crystallographic photos of muscle taken by Lotmar. Pauling also provides a brief update on work being conducted on Kenneth Rudall's fibrin sample.

Transcript

HUMANISM AND PEACE

Dr. W. Lotmar

Binzenhofstrasse 23

Aarau, Switzerland

Dear Dr. Lotmar:

I am glad to have your letter of January 2 about the value of the length of the b axis of the muscle diagram.

I had already noticed that there was some difficulty in indexing your line (011). The measurements that we have made on your photographs lead pretty definitely to a value for b of about 5.3 A instead of 5.65. With this value of b (011) cannot be satisfactorily explained on the basis of your unit. We have accordingly decided that the unit has to be changed. At present it seems likely that the only change necessary is to double one of the other axes. This makes a much larger unit, and the agreement with the photograph is not nearly so convincing; nevertheless I myself think that there are good structural arguments to support the choice of the new unit.

We ourselves are trying to make some samples of crystalized muscle, but do not know whether we are going to be successful or not.

As to the fibrin diagram of Rudall, we succeeded in indexing all of the reflections, with a unit that has two small axes and one very large one. I have now asked Rudall to make some more photographs, since he still has the specimen of crystallized fibrin.

I am looking forward to receiving your new reprints.

Sincerely yours,

Linus Pauling:W

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