The scrapbook is comprised primarily of photographs, and also contains programs for various campus events relating to the pharmacy fraternity of Kappa Psi, as well as the Y.W.C.A and the Annual Junior Vaudeville Show. The scrapbook also includes commencement programs from 1926, several dance cards, Homecoming game programs from 1923, tags and place cards, and a green freshman rook lid and ribbon. Also included are many newspaper clippings regarding Oregon State Pharmacy School, Rho Chi honor society, the pharmacy club, engagements of friends, events attended, and Dallas, Oregon.
In addition to documenting Ruby, Mildred, and fiance Andrew Irwin as students, the images also depict campus buildings and grounds, particularly Snell Hall and Our Lady of the Fountain. Several hiking and driving excursions are depicted, notably to the Willamette and Marys Rivers and the Oregon Coast. Identified classmates photographed include Clarence Wood, Donna Stone, Zeta Rippy, Stella Fishburn, Mary Belt, Florence Wharton, Katherine Boswell, and Esther Cottle. Campus events shown in photographs include distribution of Beaver yearbooks, Convocation, the "Burning of the Green", Campus Weekend, the Military Tournament, and Graduation. A few images of Ruby's parents and of other members of the Stafrin or Irwin family are also present.