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Interview with Linus Pauling.
Interview with Linus Pauling. August 23, 1991.
Interview by Thomas Hager for use in "Force of Nature: The Life of Linus Pauling," (Simon & Schuster, 1995).

Oxypolygelatin Not Approved for Human Use. (2:07)

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Linus Pauling: I patented with a couple of other people in the laboratory, the oxypolygelatin. I don't remember when I had the idea of making oxypolygelatin. Perhaps in 1940 or thereabouts.

Thomas Hager: And oxypolygelatin really never caught on, did it? As a plasma substitute?

Linus Pauling: Well, it wasn't approved by the Plasma Substitute Committee. And it was manufactured for veterinary use. My understanding is that it is still being manufactured in some places, but I don't have information. The Committee on Plasma Substitutes said that it shouldn't be administered, because it wasn't homogeneous, molecularly. It involves a range of molecular weights. I felt that, what difference does it make if there is a range of molecular weights, if it works?

Thomas Hager: Well, it's not as though there aren't a range of molecular weight substances in plasma anyway.

Linus Pauling: Yes. the plasma you have serum albumin with a molecular weight of about 65,000 and serum globulin with molecular weight of 160,000. So what difference does it make if there is a range of molecular weights?


Creator: Thomas Hager, Linus Pauling
Clip ID: hager2.006.3-oxypolygelatin

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Creator: Thomas Hager, Linus Pauling

Date: August 23, 1991
Genre: sound
ID: hager2.006.3
Copyright: More Information

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