"So far as I am aware, my idea in 1945 that human hemoglobinopathies exist was the first time that this idea had been expressed. Our 1949 paper was the first paper showing that there is in fact a human hemoglobinopathy, and it was followed by work leading to a great development of this field. My earlier work on the magnetic properties of hemoglobin was responsible in large part for the development of the now-accepted ideas about the binding of oxygen and carbon monoxide."
Linus Pauling. Letter to C. Lockard Conley. August 1, 1978.

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