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Page 1 Letter from Linus Pauling to William Castle. May 28, 1963.(Large Version) Pauling writes to relay his memories of the evolution of his thinking on the nature of sickle cell anemia. Among other details, Pauling notes that he first had the idea that sickle cell anemia might be a molecular disease after hearing Castle speak at a meeting of the Medical Advisory Committee. Date: May 28, 1963
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