June 12, 1944
Dr. R. B. Corey
Linus Pauling
I think that a part of our post-war program of intensive research might deal with
hemoglobin, including the study of the oxygen-equilibrium curve, the dissociation
of hemoglobin by urea, the properties of hemoglobin re-synthesized by adding heme
to globin, and so on; and that a part might also deal with porphyrins, which are important
both for hemoglobin and for chlorophyll.
What is the progress of our effort to get a new spectrophotometer for Chemistry-13?
Linus Pauling
P.S. I think that we could do a good job on elucidating the nature of the isomerization
of porphyrins. Chromatographic methods have been successfully applied by S. Aranoff
and M. Calvin, Journal of Organic Chemistry, 8, 205, (1943). They have found six
isomers, and I think that they should have isolated seven.
