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Page 2Letter from William Castle to Linus Pauling. November 29, 1946.
Castle writes to thank Pauling for his letter and to discuss sickle cell research
in greater depth. In so doing, Castle notes that the literature is full of publications
indicating that oxygen and carbon monoxide prevent blood sickling, and provides greater
details about his own work in determining the oxygen tension necessary to initiate
sickling. Castle closes by indicating that his future research interests include
measuring sickling as a function of blood viscosity.
Date: November 29, 1946
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